Epigenetic marker 5hmC opens door to studying its role in developmental disorders and disease
Nearly every cell in the human body carries a copy of the full human genome. So how is it that the cells that detect light in the human eye are so different from those of, say, the beating heart or the spleen?
Genetics
Feb 04, 2013 |
5 / 5 (1) |
0
|
Researchers develop Rx for deafness, impaired balance in mouse model of Usher syndrome
Jennifer Lentz, PhD, Assistant Professor of Otorhinolaryngology & Biocommunications and a member of the Neuroscience Center of Excellence at LSU Health Sciences Center New Orleans, is the lead author of a paper reporting ...
Genetics
Feb 04, 2013 |
not rated yet |
0
|
New method identifies genes that can predict prognoses of cancer patients
In recent years, it has been thought that select sets of genes might reveal cancer patients' prognoses. However, a study published last year examining breast cancer cases found that most of these "prognostic signatures" were ...
Genetics
Jan 25, 2013 |
not rated yet |
0
Discovery offers unprecedented look at regulation of gene expression
(Medical Xpress)—A groundbreaking technique developed at the University of Virginia School of Medicine is allowing scientists to examine histone modifications of genetic loci – a process that regulates gene expression ...
Medical research
Jan 25, 2013 |
5 / 5 (2) |
0
|
New mutations driving malignant melanoma discovered
Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't ...
Cancer
Jan 24, 2013 |
not rated yet |
0
|
A scanner for hereditary defects
Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. ...
Genetics
Jan 24, 2013 |
4 / 5 (2) |
0
|
Blood test might help guide pancreatic cancer treatment
(HealthDay)—A simple blood test might help predict a pancreatic cancer patient's chances of benefiting from chemotherapy, a small study suggests.
Cancer
Jan 23, 2013 |
5 / 5 (1) |
0
|
Personal epigenetic 'signatures' found consistent in prostate cancer patients' metastases
In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...
Cancer
Jan 23, 2013 |
not rated yet |
0
|
New test predicted presence of harmful BRCA mutations
A new multiple gene expression profile test was able to predict the presence of harmful BRCA1 or BRCA2 mutations in otherwise healthy women carrying the mutations, according to data published in Cancer Prevention Research, a jour ...
Cancer
Jan 22, 2013 |
not rated yet |
0
|
Expression, genomic patterns predict sarcoma progression
(HealthDay)—The Complexity Index in Sarcoma (CINSARC) and Genomic Index prognostic signatures are valid independent methods of assessing synovial sarcoma (SS) prognosis, according to a study published online ...
Cancer
Jan 18, 2013 |
not rated yet |
0
Hepatitis B virus promotes oncogenesis through microRNA modulation
Viruses prompt oncogenic transformation by genetically altering infected cells. Several recent studies have demonstrated that viruses alter the expression of microRNAs, non-coding RNA molecules that can block the expression ...
Diseases, Conditions, Syndromes
Jan 16, 2013 |
not rated yet |
0
Possible role for Huntington's gene discovered
About 20 years ago, scientists discovered the gene that causes Huntington's disease, a fatal neurodegenerative disorder that affects about 30,000 Americans. The mutant form of the gene has many extra DNA ...
Genetics
Jan 16, 2013 |
5 / 5 (3) |
0
|
Scientists reveal aggressive breast cancer's metastatic path
Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...
Cancer
Jan 14, 2013 |
5 / 5 (2) |
0
|
Team finds gene that promotes drug resistance in cancer
Scientists from the University of Iowa and Brigham Young University (BYU) have identified a gene that may be a target for overcoming drug resistance in cancer. The finding could not only improve prognostic and diagnostic ...
Cancer
Jan 14, 2013 |
4.8 / 5 (4) |
0
|
New technique comprehensively generates three-dimensional maps of gene expression in the brain
A research team led by Yuko Okamura-Oho and Hideo Yokota of the RIKEN Advanced Science Institute, Wako, has developed a novel technique for three-dimensional (3D) mapping of gene expression patterns onto ...
Genetics
Jan 11, 2013 |
not rated yet |
0
