Study shows underlying connection between 'good' cholesterol and collagen in heart health
(Medical Xpress)—Arterial stiffening has long been considered a major risk factor for cardiovascular disease. Keeping arteries soft and supple might reduce disease risk, but the mechanisms of how arteries ...
Cardiology
Nov 01, 2012 |
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New developments reveal a molecule with a promising function in terms of cancer treatment.
Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have focussed their efforts on ...
Cancer
Oct 30, 2012 |
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Oxidative stress and altered gene expression occurs in a metabolic liver disease model
A team of researchers under the direction of Dr. Jeffrey Teckman in the Department of Pediatrics at St. Louis University, have demonstrated that oxidative stress occurs in a genetic model of alpha-1-antitrypsin deficiency. ...
Medical research
Oct 30, 2012 |
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Genetic research may advance understanding of ethnic differences in breast cancer
For the first time, researchers have provided a direct comparison of gene expression profiles from African-American and East African breast tissue samples, according to results presented at the Fifth AACR Conference on The ...
Cancer
Oct 29, 2012 |
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Obese moms give birth to heart healthier kids following bariatric surgery
Kids born to moms who have lost a substantial amount of weight after undergoing bariatric surgery have fewer cardiovascular risk factors than their siblings who were born before the weight loss surgery.
Surgery
Oct 29, 2012 |
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Whitehead scientists identify major flaw in standard approach to global gene expression analysis
Whitehead Institute researchers report that common assumptions employed in the generation and interpretation of data from global gene expression analyses can lead to seriously flawed conclusions about gene activity and cell ...
Genetics
Oct 25, 2012 |
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Moffitt researchers identify unique immune gene signature across thousands of patients' solid tumors
(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered a unique immune gene signature that can predict the presence of microscopic lymph node-like structures in metastatic melanoma. The presence of these ...
Genetics
Oct 25, 2012 |
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Researcher investigate 2-drug synergy to treat drug-resistant chronic myeloid leukemia
(Medical Xpress)—An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together ...
Cancer
Oct 24, 2012 |
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Genes and immune system shaped by childhood poverty, stress
(Medical Xpress)—A University of British Columbia and Centre for Molecular Medicine and Therapeutics (CMMT) study has revealed that childhood poverty, stress as an adult, and demographics such as age, sex and ethnicity, ...
Genetics
Oct 18, 2012 |
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Epigenetic analysis of stomach cancer finds new disease subtypes
Researchers at the Duke-NUS Graduate Medical School in Singapore have identified numerous new subtypes of gastric cancer that are triggered by environmental factors.
Cancer
Oct 17, 2012 |
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Research could lead to new ways to ID women who have higher risk of breast cancer from low-dose radiation
(Medical Xpress)—Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have identified tissue mechanisms that may influence a woman's susceptibility or resistance ...
Cancer
Oct 16, 2012 |
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New gene test flags risk of serious complications in sarcoidosis
(Medical Xpress)—Researchers at the University of Illinois Hospital & Health Sciences System have identified a genetic signature that distinguishes patients with complicated sarcoidosis, an inflammatory lung disease that ...
Cancer
Oct 12, 2012 |
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Gene variant linked with reduced lung cancer risk
A variant in a gene involved with inflammation and the immune response is linked with a decreased risk of lung cancer. That is the finding of an analysis published early online in Cancer, a peer-reviewed journal of the Am ...
Cancer
Oct 08, 2012 |
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Study investigates genetic variants' role in increasing Parkinson's disease risk
Boston University School of Medicine (BUSM) investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease (PD). The study, which is published online in PLOS ONE, points to the ...
Parkinson's & Movement disorders
Oct 06, 2012 |
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Notch control of cell architecture: Potential implications for future cancer therapy
Dissecting the mechanisms implicated in cell architecture should provide new insights for understanding development and tissue morphogenesis in general. An European study focused on the role of the Notch ...
Cancer
Oct 05, 2012 |
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