Genetic studies of diseases map segments of the genome driving disease. But to understand how those changes contribute to disease progression, it is important to understand how they may alter gene regulation of disease genes ...
Apr 9, 2024
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For the first time, researchers from the University of Queensland (UQ) have mapped out the proteins implicated in the early stages of motor neuron disease (MND).
Feb 20, 2024
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Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21.
Jan 24, 2024
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Researchers from Children's Hospital of Philadelphia (CHOP) have used advanced three-dimensional mapping techniques at a microscopic level to identify a multitude of genetic variants and corresponding target gene pairings ...
Sep 6, 2022
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A newly constructed map of the landscape of genetic changes in chronic lymphocytic leukemia (CLL), a type of cancer of the blood and bone marrow that exists in diverse forms and arises from various causes, provides a better ...
Aug 4, 2022
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The findings, published today in Nature Neuroscience, represent the first time that researchers have been able to apply the discipline and tools of genetic research to brain samples from hundreds of patients with bipolar ...
Mar 7, 2022
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Using a technique called spatial transcriptomics, researchers at Karolinska Institutet have analyzed the gene expression in the mouse colon and created a map showing where in the tissue individual genes are expressed. When ...
Feb 11, 2022
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The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.
Dec 21, 2020
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Cancer mutations often incapacitate critically important genes, forcing tumors to depend heavily on other genes for survival. Such genetic dependencies are attractive targets for new cancer therapies.
Dec 16, 2020
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Cold Spring Harbor Laboratory Professor Anthony Zador has taken the next step in his quest to solve exactly how the brain is wired.
Oct 17, 2019
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