Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway
When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...
Genetics
May 14, 2013 |
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Analysing meningitis genes to identify new treatments
Scientists at the University of Liverpool are working to identify genes involved in the development of bacterial meningitis to support the search for new vaccine candidates.
Diseases, Conditions, Syndromes
Apr 19, 2013 |
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Science surprise: Toxic protein made in unusual way may explain brain disorder
A bizarre twist on the usual way proteins are made may explain mysterious symptoms in the grandparents of some children with mental disabilities.
Neuroscience
Apr 18, 2013 |
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Mutations in VCP gene implicated in a number of neurodegenerative diseases
New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone a ...
Neuroscience
Mar 14, 2013 |
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Report supports tackling tobacco consumption, improving vaccination access to reduce global cancer burden
Combating the tobacco industry's tactics in the world's poorest countries as well as ensuring the best cancer vaccines are available to those most in need are key in order to reduce the number of cancer deaths worldwide, ...
Cancer
Mar 07, 2013 |
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Mechanisms regulating inflammation associated with type 2 diabetes, cancer identified
A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation. Utilizing molecular analyses of gene expression ...
Immunology
Mar 01, 2013 |
4.8 / 5 (6) |
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Researchers find that two antagonistic proteins help keep leukemia at bay, pointing to new potential treatments
Two proteins that scientists once thought carried out the same functions are actually antagonists of each other, and keeping them in balance is key to preventing diseases such as cancer, according to new findings published ...
Cancer
Feb 27, 2013 |
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Excess protein linked to development of Parkinson's disease
Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the ...
Parkinson's & Movement disorders
Feb 07, 2013 |
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Study uncovers key to antidepressant response
Through a series of investigations in mice and humans, Johns Hopkins researchers have identified a protein that appears to be the target of both antidepressant drugs and electroconvulsive therapy. Results ...
Psychology & Psychiatry
Feb 07, 2013 |
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Gene variants found to affect human lifespan
By broadly comparing the DNA of children to that of elderly people, gene researchers have identified gene variants that influence lifespan, either by raising disease risk or by providing protection from disease.
Genetics
Feb 04, 2013 |
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New biomarker may help in detecting gliomas
Researchers using sophisticated genetic testing techniques have identified a promising new biomarker for diagnosis of glioma—the most common type of malignant brain tumor, reports the January issue of Neurosurgery, official journal of the Congres ...
Cancer
Jan 16, 2013 |
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New findings in the search for genetic clues to insulin production
In research published online Dec. 23, 2012 in the journal Nature Genetics, scientists have found three new and relatively rare genetic variants that influence insulin production, offering new clues about ...
Genetics
Dec 23, 2012 |
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Study identifies 75 genetic regions that influence red blood cell formation
New research is revealing how red blood cells are made and how the body regulates the amount of haemoglobin that is packaged in red blood cells at any time. Genomic analysis techniques have doubled the number of genetic regions ...
Genetics
Dec 05, 2012 |
4.7 / 5 (3) |
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Neuroblastoma patients with ARID1A and ARID1B mutations have more aggressive disease
In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A ...
Genetics
Dec 02, 2012 |
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Non-coding antisense RNA can be used to stimulate protein production
While studying Parkinson's disease, an international research group made a discovery which can improve industrial protein synthesis for therapeutic use. They managed to understand a novel function of non-protein ...
Genetics
Oct 16, 2012 |
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