A large team of researchers affiliated with several institutions in the U.S. and one in Germany has found evidence that makes a case for a dominant-negative effect with TP53 mutations. In their paper published in the journal ...
University of Virginia scientists have demonstrated that neurons in the brain that have been supplemented with a synthetic gene can be remotely manipulated by a magnetic field. The finding has implications for possible future ...
Mar 7, 2016
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Melbourne researchers have made a major step forward in understanding how changes in an essential cellular process, called minor class splicing, may cause a severe developmental disease.
Feb 10, 2014
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(Medical Xpress)—To survive in cold environments, mammals burn fat to produce heat. The breakdown of fat helps prevent obesity and related metabolic diseases, such as diabetes. Bruce Spiegelman and his colleagues at Harvard ...
A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28, which is implicated ...
Sep 4, 2012
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Cockayne syndrome is a severe autosomal recessive disorder caused by defective DNA repair mechanisms. People with the disease have much reduced life expectancy and suffer from facial deformities; growth failure; neurological, ...
Apr 10, 2024
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Surveys show most men in the United States are interested in using male contraceptives, yet their options remain limited to unreliable condoms or invasive vasectomies. Recent attempts to develop drugs that block sperm production, ...
Feb 20, 2024
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A new study has provided insights into an important biological mechanism that supports survival of aggressive, hard-to-treat cancers, and in the process, has uncovered fascinating new information about how cells divide and ...
Aug 30, 2023
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Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers at DZNE have come to this conclusion based on studies of cell cultures. In ...
Aug 21, 2023
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A new study published in Science Translational Medicine has found that in women with BRCA gene mutations, having a high body mass index (BMI) is linked to more DNA damage in breast cells. Specifically, the study discovered ...
