News tagged with gene regulation
The compound in the Mediterranean diet that makes cancer cells 'mortal'
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
Cancer
22 hours ago |
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Study shows potential new way to detect colorectal and other cancers
A unique new study led by University of Kentucky Markey Cancer Center researchers Guo-Min Li and Libya Gu, in collaboration with Dr. Wei Yang at National Institutes of Health, reveals a novel mechanism explaining the previously ...
Cancer
Apr 25, 2013 |
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One step closer to understanding biology behind genetic variants linked to blood cell traits
(Medical Xpress)—Researchers at the Wellcome Trust Sanger Institute and University of Cambridge have unpicked genetic variants that affect the formation of blood cells. They found that around a third of ...
Genetics
Apr 17, 2013 |
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Study identifies new gene variations associated with heart rate
Through a collaborative genome-wide study on individuals, researchers have discovered 14 new genetic variations that are associated with heart rate. Since heart rate is a marker of cardiovascular health, these findings could ...
Genetics
Apr 14, 2013 |
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Weight loss surgery not only shrinks waists but also affects genes
Gastric bypass surgery can drastically reduce the body weight of obese individuals in a short timeframe. For reasons that are not entirely clear, the surgery also leads to early remission of type 2 diabetes in the vast majority ...
Medical research
Apr 11, 2013 |
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Genetic master controls expose cancers' Achilles' heel
In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...
Cancer
Apr 11, 2013 |
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Faulty gene regulation triggers the kidney disease FSGS
The Clinical Institute of Pathology at the MedUni Vienna has discovered a previously unknown mechanism in the regulation of gene expression that leads to the development of a chronic renal condition known ...
Diseases, Conditions, Syndromes
Mar 20, 2013 |
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Not dead yet: Junk DNA is back
A controversy at last: most of our DNA is junk, no it isn't, yes it is. Actually, I think it is – up to 90% really is junk.
Genetics
Mar 15, 2013 |
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Mechanisms regulating inflammation associated with type 2 diabetes, cancer identified
A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation. Utilizing molecular analyses of gene expression ...
Immunology
Mar 01, 2013 |
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Life experiences put their stamp on the next generation: New insights from epigenetics
The 18th century natural philosopher Jean-Baptiste Lamarck proposed that the necks of giraffes lengthened as a consequence of the cumulative effort, across generations, to reach leaves just out of their grasp. This view of ...
Psychology & Psychiatry
Feb 14, 2013 |
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Long noncoding RNAs control development of fat cells
Whitehead Institute researchers have identified a previously unrecognized layer of genetic regulation that is necessary for the generation of undesirable white fat cells. When this regulation is disrupted, white fat cells ...
Overweight and Obesity
Feb 13, 2013 |
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Long memories in brain activity explain streaks in individual behaviour
(Medical Xpress)—Even with a constant task, human performance fluctuates in time-scales from seconds to minutes in a fractal manner. In a recent study a Finnish research group found that the individual variability in the ...
Neuroscience
Feb 12, 2013 |
3 / 5 (3) |
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First-in-man study demonstrates the therapeutic effect of RNAi gene silencing in cancer treatment
A study led by Dr Josep Tabernero, the Director of Clinical Research at the Vall d'Hebron Institute of Oncology (VHIO) and Head of the Medical Oncology Department at the Vall d'Hebron University Hospital, shows for the first ...
Cancer
Feb 11, 2013 |
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Study identifies liver gene that regulates cholesterol and fat blood levels
Researchers have identified a microRNA liver gene, miR-27b, which regulates lipid (cholesterol or fat) levels in the blood. This regulator gene controls multiple genes involved in dyslipidemia—abnormal blood cholesterol ...
Genetics
Feb 07, 2013 |
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One of the key circuits in regulating genes involved in producing blood stem cells is deciphered
Researchers from the group on stem cells and cancer at IMIM (Hospital del Mar Medical Research Institute) have deciphered one of the gene regulation circuits which would make it possible to generate hematopoietic blood cells, ...
Genetics
Jan 31, 2013 |
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Regulation of gene expression
Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.
Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.
Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.
Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.
For more information about Regulation of gene expression, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.