News tagged with gene switch
New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice
(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...
Cancer
May 08, 2013 |
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New genetic link found between normal fetal growth and cancer
Two researchers at the National Institutes of Health discovered a new genetic link between the rapid growth of healthy fetuses and the uncontrolled cell division in cancer. The findings shed light on normal development and ...
Genetics
Apr 09, 2013 |
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Scientists reveal aggressive breast cancer's metastatic path
Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...
Cancer
Jan 14, 2013 |
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Liver controls wasting in cancer: Overactive gene switch in the liver causes blood fat levels to drop
Many cancer patients suffer from a dramatic loss of fat and muscle mass. This extreme wasting, or cachexia, is often the actual cause of death in cancer patients. Heidelberg scientists have now discovered in mice that tumors ...
Cancer
Jan 14, 2013 |
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The X factor in liver metabolism
After you eat, your liver switches from producing glucose to storing it. At the same time, a cellular signaling pathway known as the unfolded protein response (UPR) is transiently activated, but it is not clear how this pathway ...
Medical research
Dec 21, 2012 |
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Researchers find new culprit in castration-resistant prostate cancer
Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They ...
Cancer
Dec 13, 2012 |
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Researchers highlight potential gene therapy approach to sickle cell disease
Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) have taken the first preliminary steps toward developing a form of gene therapy for sickle cell disease. In an abstract presented on Dec. 10 at the 54th ...
Medical research
Dec 11, 2012 |
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More than 3,000 epigenetic switches control daily liver cycles
(Medical Xpress)—When it's dark, and we start to fall asleep, most of us think we're tired because our bodies need rest. Yet circadian rhythms affect our bodies not just on a global scale, but at the level ...
Genetics
Dec 11, 2012 |
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Genetic switch shuts down lung cancer tumors in mice
Yale researchers manipulated a tiny genetic switch and halted growth of aggressive lung cancer tumors in mice and even prevented tumors from forming.
Cancer
Oct 25, 2012 |
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Researchers develop editing toolkit for customizing zebrafish genomes
Mayo Clinic researchers and an international team of scientists have developed a highly-efficient means of editing zebrafish genomes for research purposes, eliminating a bottleneck that has stymied biomedical scientists from ...
Genetics
Sep 23, 2012 |
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Molecular switch identified that controls key cellular process
The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.
Medical research
Aug 01, 2012 |
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Researchers discover biomarkers for prostate cancer detection, recurrence
Alterations to the "on-off" switches of genes occur early in the development of prostate cancer and could be used as biomarkers to detect the disease months or even years earlier than current approaches, a Mayo Clinic study ...
Cancer
May 14, 2012 |
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Geisel researchers sift through 'junk' to find colorectal cancer clues
Two researchers at the Geisel School of Medicine at Dartmouth have helped to identify switches that can turn on or off genes associated with colorectal cancer. The finding offers clues about the development of colorectal ...
Cancer
May 03, 2012 |
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New study shows promise for developing new treatments for breast cancer
A new study by University of Kentucky researchers provides insight into developing new treatment strategies for basal-like breast cancer, commonly known as triple-negative breast cancer. This cancer is associated with early ...
Cancer
Mar 14, 2012 |
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New system finds prostate cancer spread earlier than conventional imaging
Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed a way to image the spread of a particularly dangerous form of prostate cancer earlier than conventional imaging in use today, which may allow oncologists ...
Cancer
Sep 22, 2011 |
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