The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed ...
Jun 4, 2021
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A new, rapid screening approach uses CRISPR/Cas9 technology to identify immune system-related genes that play a crucial role in repairing zebrafish spinal cord injuries. Marcus Keatinge and Themistoklis Tsarouchas of the ...
Apr 29, 2021
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Researchers at HSE University have identified the genes that play a crucial role in breast cancer metastasis. The results of the study were published in the journal PLOS ONE.
Apr 14, 2021
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Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with a wide range of diseases. But these studies often fall short of establishing what a genetic variant does to bring ...
Apr 8, 2021
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A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg-Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new ...
Mar 1, 2021
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A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene ...
Feb 10, 2021
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Among patients with lung cancer from Latin America, genomic and ancestry analyses revealed that Native American ancestry was associated with increased mutations in the EGFR gene, independent of smoking status, according to ...
Dec 2, 2020
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A Swedish study has identified 17 new genes that could be targeted for treatment of psoriasis and eczema, two common hereditary skin diseases with no cure.
Oct 27, 2020
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A novel agent that targets a mutated form of the KRAS gene—the most commonly altered oncogene in human cancers and one long considered "undruggable"—shrank tumors in most patients in a clinical trial with manageable side ...
Oct 25, 2020
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Researchers at the Institut de Recerca Sant Joan de Déu (IRSJD) in collaboration with those at Center for Genomic Regulation (CRG) have discovered that RING1B is a critical gene for the development of Ewing sarcoma, a rare ...
Oct 23, 2020
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