News tagged with gene therapies
Understanding 'master regulator' genes could lead to better cancer treatments
A pair of genes work together as "master regulators" in cell division to keep the correct number of chromosomes in each daughter cell. Ipl1 and Mps1 work to hook and unhook chromosomes for proper DNA separation. The discovery ...
Genetics
Jan 31, 2013 |
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Researchers find gene that turns up effect of chemotherapy
Chemotherapy is one of the most common treatments for cancer patients. However, many patients suffer from serious side-effects and a large proportion does not respond to the treatment. Researchers from the Biotech Research ...
Cancer
Jan 29, 2013 |
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Altering eye cells may one day restore vision
(Medical Xpress)—Doctors may one day treat some forms of blindness by altering the genetic program of the light-sensing cells of the eye, according to scientists at Washington University School of Medicine ...
Ophthalmology
Jan 25, 2013 |
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Canada launches first gene therapy trial for Fabry disease
Researchers in Calgary have launched the first gene therapy clinical trial in the world for Fabry disease, a rare inherited enzyme deficiency that can shorten the lifespan of people who have it by as much as 40 years.
Diseases, Conditions, Syndromes
Jan 24, 2013 |
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New study sheds light on the complexity of gene therapy for congenital blindness
Independent clinical trials, including one conducted at the Scheie Eye Institute at the Perelman School of Medicine, have reported safety and efficacy for Leber congenital amaurosis (LCA), a congenital form of blindness caused ...
Genetics
Jan 22, 2013 |
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Immune cells engineered in lab to resist HIV infection
Researchers at the Stanford University School of Medicine have found a novel way to engineer key cells of the immune system so they remain resistant to infection with HIV, the virus that causes AIDS.
HIV & AIDS
Jan 22, 2013 |
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Australian study turns HIV against itself (Update)
An Australian scientist said Wednesday he had discovered a way to turn the HIV virus against itself in human cells in the laboratory, in an important advance in the quest for an AIDS cure.
HIV & AIDS
Jan 16, 2013 |
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A quantum leap in gene therapy of Duchenne muscular dystrophy
Usually, results from a new study help scientists inch their way toward an answer whether they are battling a health problem or are on the verge of a technological breakthrough. Once in a while, those results ...
Medical research
Jan 15, 2013 |
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Carolina scientists use virus to deliver genetic material to slow kids' illness
Even if the patients hadn't been as young as 4 months old, the surgery would have been harrowing: six holes bored into the skull, six tiny tubes inserted directly into targeted parts of the brain, then a solution containing ...
Medical research
Jan 14, 2013 |
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Rebuilding blood vessels through gene therapy
(Medical Xpress)—Diagnosed with severe coronary artery disease, a group of patients too ill for or not responding to other treatment options decided to take part in a clinical trial testing angiogenic gene therapy to help ...
Cardiology
Dec 21, 2012 |
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Two novel treatments for retinitis pigmentosa move closer to clinical trials
Two recent experimental treatments—one involving skin-derived induced pluripotent stem (iPS) cell grafts, the other gene therapy—have been shown to produce long-term improvement in visual function in mouse models of retinitis ...
Ophthalmology
Dec 20, 2012 |
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Gene therapy cocktail shows promise in long-term clinical trial for rare fatal brain disorder
Results of a clinical trial that began in 2001 show that a gene therapy cocktail conveyed into the brain by a molecular special delivery vehicle may help extend the lives of children with Canavan disease, a rare and fatal ...
Medical research
Dec 19, 2012 |
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Cancer study overturns current thinking about gene activation
(Medical Xpress)—A new Australian study led by Professor Susan Clark from Sydney's Garvan Institute of Medical Research shows that large regions of the genome – amounting to roughly 2% – are epigenetically activated ...
Cancer
Dec 18, 2012 |
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Team inhibits Alzheimer's biomarkers in animal model by targeting astrocytes
A research team composed of University of Kentucky researchers has published a paper which provides the first direct evidence that activated astrocytes could play a harmful role in Alzheimer's disease. The UK Sanders-Brown ...
Alzheimer's disease & dementia
Dec 11, 2012 |
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Researchers highlight potential gene therapy approach to sickle cell disease
Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) have taken the first preliminary steps toward developing a form of gene therapy for sickle cell disease. In an abstract presented on Dec. 10 at the 54th ...
Medical research
Dec 11, 2012 |
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