When the Human Genome Project was completed, in 2003, it opened the door to a radical new idea of health—that of personalized medicine, in which disease risk and appropriate treatment would be gleaned from one's genetic ...
Mar 25, 2019
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Spider-like cells inside the brain, spinal cord and eye hunt for invaders, capturing and then devouring them. These cells, called microglia, often play a beneficial role by helping to clear trash and protect the central nervous ...
Jul 2, 2015
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Two new genes that raise a person's risk of developing Alzheimer's Disease have been discovered by researchers.
Nov 22, 2022
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Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear ...
Oct 15, 2021
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BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instances, leading to breast and ovarian cancer, plays an important role in the body's DNA repair mechanisms. BRCA1, once mutated, can cause cancer to develop. ...
Nov 17, 2022
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Scientists at Scripps Research in Jupiter have developed a special molecular switch that could be embedded into gene therapies to allow doctors to control dosing.
Dec 24, 2019
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Researchers at the São Paulo State Cancer Institute (ICESP) in Brazil have used a genetically manipulated virus to destroy tumor cells upon injection into mice with prostate cancer. The virus also made tumor cells more sensitive ...
Jun 27, 2019
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Canada's first human gene therapy trial for eyes—the replacement of a faulty gene with a healthy one—is now underway at the Royal Alexandra Hospital to preserve and potentially restore vision for people with a genetic ...
Jun 29, 2015
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In a first-of-its-kind clinical study, Baylor College of Medicine evaluated the safety, survival and anti-tumor activity of tumor-specific T cells rendered resistant to transforming growth factor β (TGFβ), in patients with ...
Jan 26, 2018
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Researchers funded by the National Institutes of Health have developed a novel mouse model for the vision disorder Leber hereditary optic neuropathy (LHON), and found that they can use gene therapy to improve visual function ...
Oct 5, 2015
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