Targeted gene therapy enhances treatment for Pompe disease
Gene therapy to replace the protein missing in Pompe disease can be effective if the patient's immune system does not react against the therapy. Targeted delivery of the gene to the liver, instead of throughout the body,suppresses ...
Diseases, Conditions, Syndromes
Jun 25, 2012 |
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Researchers review muscular dystrophy therapies
Leading muscular dystrophy researcher Dean Burkin, of the University of Nevada School of Medicine summarizes the impact of a new protein therapeutic, MG53, for the treatment of Duchenne muscular dystrophy ...
Medical research
Jun 22, 2012 |
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Researchers determine 3D structure of adeno-associated virus 9: Aim to boost gene therapy
A team of researchers led by the University of Florida, Gainesville, has determined the precise structure of a virus that has promise as a delivery vehicle for gene therapy. The research appears in the June 2012 issue of ...
Genetics
Jun 21, 2012 |
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Molecule thought cancer foe actually helps thyroid tumors grow
A molecule widely believed to fight many forms of cancer actually helps deadly thyroid tumors grow, and cancer therapies now being tested in humans might boost the activity of this newly revealed bad guy, researchers at Mayo ...
Cancer
Jun 20, 2012 |
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Does night work put women's health at risk?
Breast cancer is the number one cause of female mortality. It affects 100 out of 100,000 women per year in developed countries. Each year, more than 1.3 million new cases are diagnosed, 53,000 of these in France.
Cancer
Jun 19, 2012 |
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Newly identified protein function protects cells during injury
Scientists have discovered a new function for a protein that protects cells during injury and could eventually translate into treatment for conditions ranging from cardiovascular disease to Alzheimer's.
Medical research
Jun 07, 2012 |
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Gene therapy can correct forms of severe combined immunodeficiency
Severe combined immunodeficiency is defect in the immune system that results in a loss of the adaptive immune cells known as B cells and T cells. Mutations in several different genes can lead to the development of severe ...
Immunology
May 24, 2012 |
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Scientists unravel role of fusion gene in prostate cancer
Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein -- but no one has known how that alteration promotes cancer growth. Now, Weill ...
Cancer
May 22, 2012 |
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Children with rare, incurable brain disease improve after gene therapy
Using gene transfer techniques pioneered by University of Florida faculty, Taiwanese doctors have restored some movement in four children bedridden with a rare, life-threatening neurological disease.
Pediatrics
May 16, 2012 |
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Delivery of gene-therapy for heart disease boosted 100-fold; now in 100-patient trial
Cardium Therapeutics today announced a late-breaking poster presentation at the American Society of Gene & Cell Therapy (ASGCT) 15th Annual Meeting being held May 16-19, 2012 at the Pennsylvania Convention ...
Cardiology
May 16, 2012 |
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Scientists successfully test first gene therapy against aging-associated decline
A number of studies have shown that it is possible to lengthen the average life of individuals of many species, including mammals, by acting on specific genes. To date, however, this has meant altering the animals' genes ...
Genetics
May 14, 2012 |
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Molecular subtypes and genetic alterations may determine response to lung cancer therapy
Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient's individual molecular profile. But scientists are finding that in many types of cancer the molecular ...
Cancer
May 11, 2012 |
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Gene therapy for hearing loss: Potential and limitations
Regenerating sensory hair cells, which produce electrical signals in response to vibrations within the inner ear, could form the basis for treating age- or trauma-related hearing loss. One way to do this could be with gene ...
Neuroscience
May 11, 2012 |
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New advances in treating inherited retinal diseases highlighted in Human Gene Therapy
Gene therapy strategies to prevent and treat inherited diseases of the retina that can cause blindness have progressed rapidly. Positive results in animal models of human retinal disease continue to emerge, ...
Genetics
May 08, 2012 |
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T cell-based HIV gene therapy safe over long term
(HealthDay) -- T cell-based gene therapy for HIV seems safe, with no evidence of vector-induced cell immortalization more than a decade after treatment, according to a study published in the May 2 issue of ...
HIV & AIDS
May 07, 2012 |
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