Oncology & Cancer

Change in a single DNA base drives a childhood cancer

Pediatric oncology researchers have pinpointed a crucial change in a single DNA base that both predisposes children to an aggressive form of the childhood cancer neuroblastoma and makes the disease progress once tumors form.

Genetics

Signaling to chromatin

(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) in collaboration with their colleagues from the Department of Biosystems Science and Engineering of the ETH Zurich, describe ...

Attention deficit disorders

Working out the genetic risk for ADHD

Genetics play a strong part in the development of attention-deficit/hyperactivity disorder (ADHD), but the path from a gene to risk for the disorder has remained a black box to researchers.. A new study in Biological Psychiatry ...

Genetics

The unfolding 'SAGA' of transcriptional co-activators

Successful gene expression requires the concerted action of a host of regulatory factors. Long overshadowed by bonafide transcription factors, coactivators—the hanger-ons that facilitate transcription by docking onto ...

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