A history lesson from genes: Using DNA to tell us how populations change
When Charles Darwin first sketched how species evolved by natural selection, he drew what looked like a tree. The diagram started at a central point with a common ancestor, then the lines spread apart as ...
Genetics
Jan 09, 2013 |
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Chromatin marks the spot in search for disease pathways
In September 2012, the Encyclopedia of DNA Elements (ENCODE) Project Consortium, a multi-institution collaboration that included the Broad Institute, capped off nine years of research with a flurry of papers ...
Genetics
Jan 07, 2013 |
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Study suggests human genes influence gut microbial composition
New research led by the Karolinska Institutet, Sweden and the University of Glasgow, Scotland, has identified a link between a human gene and the composition of human gastrointestinal bacteria. In a study published as a letter ...
Medical research
Jan 07, 2013 |
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Dopamine-receptor gene variant linked to human longevity
(Medical Xpress)—A variant of a gene associated with active personality traits in humans seems to also be involved with living a longer life, UC Irvine and other researchers have found.
Neuroscience
Jan 03, 2013 |
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Study suggests gene variation may shape bladder cancer treatment
(Medical Xpress)—Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic ...
Cancer
Dec 27, 2012 |
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New findings in the search for genetic clues to insulin production
In research published online Dec. 23, 2012 in the journal Nature Genetics, scientists have found three new and relatively rare genetic variants that influence insulin production, offering new clues about ...
Genetics
Dec 23, 2012 |
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Genomic 'hotspots' offer clues to causes of autism, other disorders
An international team, led by researchers from the University of California, San Diego School of Medicine, has discovered that "random" mutations in the genome are not quite so random after all. Their study, ...
Genetics
Dec 20, 2012 |
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A genetic defect in sex cells may predispose to childhood leukemia
Researchers at the Sainte-Justine University Hospital Center and the University of Montreal have found a possible heredity mechanism that predisposes children to acute lymphoblastic leukemia (ALL), the most ...
Genetics
Dec 17, 2012 |
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Gene-environment interaction ups risk of preeclampsia
(HealthDay)—A genetic variant, AGT2R, in mothers, fathers, and neonates is associated with a significantly increased risk of preeclampsia in mothers with a body mass index (BMI) of 25 kg/m² or more, accord ...
Health
Dec 10, 2012 |
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Researchers produce a catalog of the deleterious and disease-causing genetic variants in healthy people
Researchers at Cambridge and Cardiff have found that, on average, a normal healthy person carries approximately 400 potentially damaging DNA variants and two variants known to be associated directly with disease traits. They ...
Genetics
Dec 06, 2012 |
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Scientists identify molecules in the ear that convert sound into brain signals
For scientists who study the genetics of hearing and deafness, finding the exact genetic machinery in the inner ear that responds to sound waves and converts them into electrical impulses, the language of ...
Medical research
Dec 06, 2012 |
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A new genetic fingerprint lives in your belly
Our bodies contain far more microbial genes than human genes. And a new study suggests that just as human DNA varies from person to person, so too does the massive collection of microbial DNA in the intestine.
Medical research
Dec 05, 2012 |
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Harmful protein-coding mutations in people arose largely in the past 5,000 to 10,000 years (Update)
(Medical Xpress)—A study dating the age of more than 1 million single-letter variations in the human DNA code reveals that most of these mutations are of recent origin, evolutionarily speaking. These kinds ...
Genetics
Nov 28, 2012 |
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Research identifies a genetic cause of hypertension
(Medical Xpress)—A multinational research project led by the Universities of Dundee and Glasgow has identified a genetic determinant of hypertension (or high blood pressure), which could inform treatment of the condition ...
Cardiology
Nov 22, 2012 |
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Skin cells reveal DNA's genetic mosaic
(Medical Xpress)—The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread ...
Genetics
Nov 19, 2012 |
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