New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice
(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...
Cancer
May 08, 2013 |
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Researchers discover possible trigger for spread of head and neck cancer cells
(Medical Xpress)—Very little has been known about the epigenetic events—developmental and environmental factors affecting genes—that occur prior to the invasive growth of head and neck squamous cell carcinomas and their ...
Cancer
May 08, 2013 |
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Gene test may help guide prostate cancer treatment
A new genetic test to gauge the aggressiveness of prostate cancer may help tens of thousands of men each year decide whether they need to treat their cancer right away or can safely monitor it.
Genetics
May 08, 2013 |
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Amplification of a Stat5 gene produces excess oncogenic protein that drives prostate cancer spread
An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells ...
Cancer
May 07, 2013 |
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Genetic variations associated with susceptibility to bacteria linked to stomach disorders
Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and st ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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MicroRNA cooperation mutes breast cancer oncogenes
A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot ...
Cancer
May 07, 2013 |
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New test methods can reduce the amount of animal testing
Making more use of in-vitro testing, the upcoming 21st-century scientific fields known as 'omics' sciences and developing smart test strategies can clearly reduce the amount of essential animal testing. This ...
Medical research
May 07, 2013 |
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Geneticists find causes for severe childhood epilepsies
(Medical Xpress)—Using a state-of-the-art DNA sequencing technique, UA researchers have discovered genetic mutations underlying seizure disorders in previously undiagnosed children.
Neuroscience
May 07, 2013 |
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New perspective needed for role of major Alzheimer's gene
(Medical Xpress)—Scientists' picture of how a gene strongly linked to Alzheimer's disease harms the brain may have to be revised, researchers at Washington University School of Medicine in St. Louis have found.
Medical research
May 07, 2013 |
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Scientists find clues to some inherited heart diseases
(Medical Xpress)—Cornell researchers have uncovered the basic cell biology that helps explain heart defects found in diseases known as laminopathies, a group of some 15 genetic disorders that include forms ...
Medical research
May 07, 2013 |
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tPA: Clot buster and brain protector
(Medical Xpress)—Ever since its introduction in the 1990s, the "clot-busting" drug tPA has been considered a "double-edged sword" for people experiencing a stroke. It can help restore blood flow to the ...
Neuroscience
May 07, 2013 |
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Researchers identify critical link in mammalian odor detection
Researchers at the Monell Center and collaborators have identified a protein that is critical to the ability of mammals to smell. Mice engineered to be lacking the Ggamma13 protein in their olfactory receptors were functionally ...
Neuroscience
May 06, 2013 |
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Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
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Activity of cancer inducing genes can be controlled by the cell's skeleton
Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis. ...
Cancer
May 06, 2013 |
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ECE: Gene variants linked to reduced male fertility
(HealthDay)—Particular gene variants of follicle stimulating hormone (FSH) and its receptor are associated with significantly reduced fertility in men, according to a study presented at the annual European ...
Genetics
May 03, 2013 |
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