Deficiency in p53 anti-tumor protein delays DNA repair after radiation
Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...
Cancer
Apr 23, 2013 |
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A noninvasive avenue for Parkinson's disease gene therapy
Researchers at Northeastern University in Boston have developed a gene therapy approach that may one day stop Parkinson's disease (PD) in it tracks, preventing disease progression and reversing its symptoms. The novelty of ...
Parkinson's & Movement disorders
Apr 21, 2013 |
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Large animal models of Huntington's disease offer new and promising research options
Scientific progress in Huntington's disease (HD) relies upon the availability of appropriate animal models that enable insights into the disease's genetics and/or pathophysiology. Large animal models, such as domesticated ...
Neuroscience
Apr 22, 2013 |
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The gene therapy renaissance: How experimental technique overcame a troubled legacy and is now helping the blind to see
(Medical Xpress)—In 1999, researchers at the University of Pennsylvania injected 19 people with a virus carrying a gene designed to correct a rare metabolic disease. Early results appeared promising: Among ...
Genetics
Apr 19, 2013 |
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Scientists find ethnicity linked to antibodies
(Medical Xpress)—Cracking the DNA code for a complex region of the human genome has helped 14 North American scientists, including five at Simon Fraser University, chart new territory in immunity research.
Genetics
Apr 17, 2013 |
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Particular DNA changes linked with prostate cancer development and lethality
A new analysis has found that the loss or amplification of particular DNA regions contributes to the development of prostate cancer, and that patients with two of these DNA changes have a high likelihood of dying from the ...
Cancer
Apr 22, 2013 |
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Vitamin A could prevent the spread of prostate cancer
(Medical Xpress)—Vitamin A could help treat and prevent the spread of prostate cancer, according to research published today (Monday, April 15th) in Oncogenesis.
Cancer
Apr 16, 2013 |
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Microglia derived from patient-specific human-induced pluripotent stem cells
Today, during the 81st American Association of Neurological Surgeons (AANS) Annual Scientific Meeting, researchers announced new findings regarding the development of methods to turn human induced pluripotent stem cells (iPSC) ...
Medical research
May 02, 2013 |
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Analysing meningitis genes to identify new treatments
Scientists at the University of Liverpool are working to identify genes involved in the development of bacterial meningitis to support the search for new vaccine candidates.
Diseases, Conditions, Syndromes
Apr 19, 2013 |
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Science surprise: Toxic protein made in unusual way may explain brain disorder
A bizarre twist on the usual way proteins are made may explain mysterious symptoms in the grandparents of some children with mental disabilities.
Neuroscience
Apr 18, 2013 |
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Team taps the wisdom of the crowd to impact breast cancer prognosis
Two new reports issuing in Science Translational Medicine (STM) today showcase the potential of teams of scientists working together to solve increasingly complex medical problems. The results demonstrate that better predic ...
Cancer
Apr 17, 2013 |
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Family history of Alzheimer's associated with abnormal brain pathology
Close family members of people with Alzheimer's disease are more than twice as likely as those without a family history to develop silent buildup of brain plaques associated with Alzheimer's disease, according to researchers ...
Alzheimer's disease & dementia
Apr 17, 2013 |
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New computational model can predict breast cancer survival
Columbia Engineering researchers, led by Dimitris Anastassiou, Charles Batchelor Professor in Electrical Engineering and member of the Columbia Initiative in Systems Biology, have developed a new computational model that ...
Cancer
Apr 17, 2013 |
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Clinical trials helped one woman's fight against cancer
(HealthDay)—Monica Barlow, a 35-year-old from Maryland, was training for a half-marathon when she noticed she couldn't shake a bad cough and ongoing fatigue. After a couple of rounds of antibiotics from ...
Cancer
Apr 18, 2013 |
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Discovery of genetic defect that triggers epilepsy
Researchers at the University Department of Neurology at the MedUni Vienna have identified a gene behind an epilepsy syndrome, which could also play an important role in other idiopathic (genetically caused) ...
Neuroscience
Apr 17, 2013 |
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