Key mechanism for a common form of Alzheimer's disease discovered
Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...
Alzheimer's disease & dementia
Apr 25, 2013 |
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Viral Vectors delivery new calcium pumps for ailing hearts
(Medical Xpress)—A fresh round of trials to evaluate gene therapy for the heart is set to begin in a couple of weeks. The British Heart Foundation will be sponsoring the study, which seeks to replace defective ...
Medical research
May 01, 2013 |
4.2 / 5 (5) |
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Scientists find new gene markers for cancer risk
A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian ...
Genetics
Mar 27, 2013 |
5 / 5 (4) |
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Scientists find potential loophole in pancreatic cancer defenses
Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control ...
Cancer
Mar 27, 2013 |
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Researchers discover new clues about how amyotrophic lateral sclerosis develops
Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis (ALS), a ...
Neuroscience
Mar 31, 2013 |
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Researchers identify new potential target for cancer therapy
Researchers at UT Southwestern Medical Center have found that alternative splicing – a process that allows a single gene to code for multiple proteins – appears to be a new potential target for anti-telomerase ...
Cancer
Apr 19, 2013 |
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Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
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Gene thought to make heart tissues turns out to make blood and muscles as well
New research out of the Lillehei Heart Institute at the University of Minnesota shows that by turning on just a single gene, Mesp1, different cell types including the heart, blood and muscle can be created from stem cells.
Genetics
May 02, 2013 |
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Researchers identify how cells control calcium influx
(Medical Xpress)—When brain cells are overwhelmed by an influx of too many calcium molecules, they shut down the channels through which these molecules enter the cells. Until now, the "stop" signal mechanism that cells ...
Neuroscience
May 09, 2013 |
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PTSD research: Distinct gene activity patterns from childhood abuse
Abuse during childhood is different. A study of adult civilians with PTSD (post-traumatic stress disorder) has shown that individuals with a history of childhood abuse have distinct, profound changes in gene activity patterns, ...
Psychology & Psychiatry
May 01, 2013 |
4 / 5 (4) |
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Researchers form new nerve cells—directly in the brain
The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments. A new report from researchers at Lund University in ...
Neuroscience
Mar 26, 2013 |
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Novel intercellular transportation system may have potential for delivering RNAi and other gene-based therapeutics
(Medical Xpress)—Important new research from UMass Medical School demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting ...
Neuroscience
Mar 27, 2013 |
5 / 5 (3) |
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New insights into how genes turn on and off
Researchers at UC Davis and the University of British Columbia have shed new light on methylation, a critical process that helps control how genes are expressed. Working with placentas, the team discovered that 37 percent ...
Genetics
Mar 27, 2013 |
5 / 5 (3) |
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Cell reprogramming during liver regeneration
During embryonic development, animals generate many different types of cells, each with a distinct function and identity.
Medical research
Mar 28, 2013 |
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Neuroscientists show 'jumping genes' may contribute to aging-related brain defects
As the body ages, the physical effects are notable; wrinkles in the skin appear, physical exertion becomes harder. But there are also less visible processes going on. Inside aging brains there is another phenomenon at work, ...
Neuroscience
Apr 08, 2013 |
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