News tagged with genetic alteration
Mayo Clinic genomic analysis lends insight to prostate cancer
Mayo Clinic researchers have used next generation genomic analysis to determine that some of the more aggressive prostate cancer tumors have similar genetic origins, which may help in predicting cancer progression. The findings ...
Cancer
May 23, 2013 |
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Novel RNA-based classification system for colorectal cancer
A novel transcriptome-based classification of colon cancer that improves the current disease stratification based on clinicopathological variables and common DNA markers is presented in a study published in PLOS Medicine this w ...
Cancer
May 21, 2013 |
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Scientists find mutation driving pediatric brain tumors
A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at ...
Genetics
Apr 30, 2013 |
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New subtype of ataxia identified
Researchers from the Germans Trias i Pujol Health Sciences Research Institute Foundation (IGTP), the Bellvitge Biomedical Research Institute (IDIBELL), and the Sant Joan de Déu de Martorell Hospital, has identified a new ...
Neuroscience
Apr 29, 2013 |
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Three mutations at BRCA1 gene responsible for breast and ovarian hereditary cancer
Researchers of the hereditary cancer research group at the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO) conducted a functional and structural study of seven missense variants ...
Cancer
Apr 18, 2013 |
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Whole genome sequencing finds new mutations to blame for a majority of brain tumor subtype
Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients. Researchers also found evidence the tumors ...
Genetics
Apr 14, 2013 |
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The relationship between prenatal stress and obesity is confirmed in rats
The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated ...
Health
Apr 09, 2013 |
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KDM1 may represent a new therapeutic target for glioma
Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...
Cancer
Apr 08, 2013 |
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Comprehensive genomic analysis identifies alterations in head and neck cancer that could lead to targeted therapy
Not all head and neck squamous cell carcinomas (HNSCCs) have the same pattern of genomic alterations, but those cancers with certain distinctive patterns could be amenable to specific targeted therapies, according to a researcher ...
Cancer
Apr 08, 2013 |
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Legal levels of atrazine alter neuroendocrine, reproductive genes in zebrafish
(Medical Xpress)—A Purdue University study found an agricultural herbicide alters reproductive and neuroendocrine genes during embryonic development in fish, a finding that will help establish a genetic ...
Medical research
Apr 03, 2013 |
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Unique study reveals genetic 'spelling mistakes' that increase the risk of common cancers
More than 80 genetic 'spelling mistakes' that can increase the risk of breast, prostate and ovarian cancer have been found in a large, international research study within the framework of the EU Network COGS. For the first ...
Cancer
Mar 27, 2013 |
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Molecular basis identified for tissue specific immune regulation in the eye and kidney
Scientists at The University of Manchester have made important advances in understanding why our immune system can attack our own tissues resulting in eye and kidney diseases. It is hoped the research will pave the way for ...
Immunology
Feb 20, 2013 |
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Some autism behaviors linked to altered gene
Scientists at Washington University School of Medicine in St. Louis have identified a genetic mutation that may underlie common behaviors seen in some people with autism, such as difficulty communicating ...
Neuroscience
Feb 12, 2013 |
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Colon cancer exhibits a corresponding epigenetic pattern in mice and humans
Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between ...
Genetics
Feb 07, 2013 |
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Common genetic alteration found in head and neck cancers may not be key to effective treatment
Although a large majority of head and neck cancers have a deregulation of the PI3K/AKT/mTOR pathway, data recently published in Cancer Research, a journal of the American Association for Cancer Research, indicated that d ...
Cancer
Jan 29, 2013 |
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