News tagged with genetic alteration

New view of tumors' evolution

Cancer cells undergo extensive genetic alterations as they grow and spread through the body. Some of these mutations, known as "drivers," help spur cells to grow out of control, while others ("passengers") are merely along ...

Mar 13, 2014
popularity 5 / 5 (5) | comments 0

Lifestyle influences metabolism via DNA methylation

An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum München have now identified 28 DNA alterations associated with ...

Sep 20, 2013
popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Clinical trials for cancer, one patient at a time

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time. The patient's tumor is "reverse ...

Jul 15, 2013
popularity 3.7 / 5 (3) | comments 1 | with audio podcast