News tagged with genetic change


Epigenetics emerges powerfully as a clinical tool

A study coordinated by Manel Esteller, published in Nature Reviews Genetics, highlights the success of this area of research to predict the behavior and weaknesses of tumors.

Genetics created Sep 12, 2012 | popularity not rated yet | comments 0

What's the main cause of obesity—our genes or the environment?

The ongoing obesity epidemic is creating an unprecedented challenge for healthcare systems around the world, but what determines who gets fat? Two experts debate the issue in the British Medical Journal today.

Overweight and Obesity created Sep 11, 2012 | popularity not rated yet | comments 0

First evidence for genetic cause for Barrett's oesophagus found

Genetic variations that are linked with the onset of Barrett's oesophagus (BE), a pre-cancerous condition of the lower end of the gullet, have been identified for the first time. The discovery of variations in regions on ...

Genetics created Sep 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

ENCODE project: Researchers unlock disease information hidden in genome's control circuitry

Researchers at the University of Washington have determined that the majority of genetic changes associated with more than 400 common diseases and clinical traits affect the genome's regulatory circuitry. ...

Genetics created Sep 05, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Review of new evidence to treat colonic diverticulitis may help doctors

Recent evidence and new treatments for colonic diverticulitis that may help clinicians manage and treat the disease are summarized in a review in CMAJ (Canadian Medical Association Journal).

Diseases, Conditions, Syndromes created Aug 27, 2012 | popularity not rated yet | comments 0

Mechanisms of acquired chemoresistance in ovarian cancer identified

The presence of multiple ovarian cancer genomes in an individual patient and the absence or downregulation of the gene LRP1B are associated with the development of chemoresistance in women with the high-grade serous cancer ...

Cancer created Aug 15, 2012 | popularity 5 / 5 (1) | comments 0

Ten new diabetes gene links offer picture of biology underlying disease

(Medical Xpress) -- Ten more DNA regions linked to type 2 diabetes have been discovered by an international team of researchers, bringing the total to over 60.

Genetics created Aug 12, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Genomic study of rare children's cancer yields possible prognostic tool

A new study of the genetic makeup, or genome, of Ewing sarcoma, a rare cancer that strikes children, teenagers, and young adults, has produced multiple discoveries: a previously unknown sarcoma subtype, genetic factors related ...

Cancer created Aug 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Genetic copy-number variants and cancer risk

Genetics clearly plays a role in cancer development and progression, but the reason that a certain mutation leads to one cancer and not another is less clear. Furthermore, no links have been found between any cancer and a ...

Genetics created Aug 02, 2012 | popularity not rated yet | comments 0

Hundreds of random mutations in leukemia linked to aging, not cancer

Hundreds of mutations exist in leukemia cells at the time of diagnosis, but nearly all occur randomly as a part of normal aging and are not related to cancer, new research shows.

Genetics created Jul 19, 2012 | popularity 5 / 5 (5) | comments 3 | with audio podcast

New study announced that will use genetics to test for Alzheimer's risk

In a new Alzheimer's disease risk assessment study unveiled this week during the Alzheimer's Association International Conference, researchers at Brigham and Women's Hospital (BWH) are offering genetic testing and Alzheimer's ...

Alzheimer's disease & dementia created Jul 19, 2012 | popularity 5 / 5 (1) | comments 0

Gene link to multiple sclerosis

(Medical Xpress) -- The biological role of a gene variant implicated in multiple sclerosis (MS) has been determined by researchers at Oxford University.

Genetics created Jul 11, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Major new study finds clues to the genetic causes of osteoarthritis (Update)

(Medical Xpress) -- UK scientists have discovered more genetic regions associated with the cause of osteoarthritis. Researchers from nine institutions across the UK have described the findings as a significant breakthrough ...

Arthritis & Rheumatism created Jul 02, 2012 | popularity not rated yet | comments 0

Gene mutations cause massive brain asymmetry

Hemimegalencephaly is a rare but dramatic condition in which the brain grows asymmetrically, with one hemisphere becoming massively enlarged. Though frequently diagnosed in children with severe epilepsy, the ...

Cancer created Jun 24, 2012 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Cigarette smoke damages DNA in reproductive cells of fathers, these changes inherited by offspring

When shopping for dad's Father's Day gift, consider what he gave you when you were conceived. If he smoked, your genes are likely damaged, and your odds for diseases increased. A report in the FASEB Journal shows that men wh ...

Medical research created Jun 22, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast