News tagged with genetic change


The path to personalized cancer treatment

In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The study is published in Nature on Thursday 29 Mar ...

Cancer created Mar 28, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Computer simulations help explain why HIV cure remains elusive

A new research report appearing in the March 2012 issue of the journal Genetics shows why the development of a cure and new treatments for HIV has been so difficult. In the report, an Australian scientist explains how he used ...

HIV & AIDS created Mar 15, 2012 | popularity not rated yet | comments 0

Epigenetics and epidemiology -- hip, hype and science

Epigenetics is the new hip science. Time Magazine's front cover and article, 'Why your DNA isn't your Destiny' from January 2010 explains why. Its more explicit subtitle provided the hook - 'The new science of epigenetics ...

Genetics created Mar 15, 2012 | popularity not rated yet | comments 0

Cancer epigenetics: Breakthrough in ID'ing target genes

Cancer is usually attributed to faulty genes, but growing evidence from the field of cancer epigenetics indicates a key role for the gene "silencing" proteins that stably turn genes off inside the cell nucleus. ...

Cancer created Mar 13, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Exercise changes your DNA

You might think that the DNA you inherited is one thing that you absolutely can't do anything about, but in one sense you'd be wrong. Researchers reporting in the March issue of Cell Metabolism, a Cell Press publication, have f ...

Genetics created Mar 06, 2012 | popularity 5 / 5 (7) | comments 2 | with audio podcast

New research shows childhood adversity causes changes in genetics

In a look at how major stressors during childhood can change a person's biological risk for psychiatric disorders, researchers at Butler Hospital have discovered a genetic alteration at the root of the association. The research, ...

Genetics created Feb 27, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Genetic risk for elevated arsenic toxicity discovered

One of the first large-scale genomic studies conducted in a developing country has discovered genetic variants that elevate the risk for skin lesions in people chronically exposed to arsenic. Genetic changes found near the ...

Genetics created Feb 23, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Telomere failure, telomerase activation drive prostate cancer progression

Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those caps, allows malignant cells to evade destruction and acquire more deadly characteristics, ...

Cancer created Feb 21, 2012 | popularity 4 / 5 (1) | comments 0

When is a gene not a gene? New catalog helps identify gene variations associated with disease

A high-quality reference catalogue of the genetic changes that result in the deactivation of human genes has been developed by a team of researchers. This catalogue of loss-of-function (LoF) variants is needed ...

Genetics created Feb 16, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Metabolic profiles essential for personalizing cancer therapy

One way to tackle a tumor is to take aim at the metabolic reactions that fuel their growth. But a report in the February Cell Metabolism shows that one metabolism-targeted cancer therapy will not fit all. That means that m ...

Cancer created Feb 07, 2012 | popularity 4 / 5 (1) | comments 0

Mayo Clinic releases book with action plan to help beat heart disease

Heart disease is the nation's No. 1 killer for both men and women. But what's most astonishing is that almost 80 percent of heart disease is preventable, and even small lifestyle changes can have a big impact.

Health created Jan 30, 2012 | popularity 4.5 / 5 (2) | comments 0

Add some spice to your food and boost your disease-prevention power

The holidays are over, January has arrived, and many of us enter the New Year determined to live our lives a little healthier than last.

Health created Jan 06, 2012 | popularity 4.5 / 5 (2) | comments 1

First comprehensive DNA study of mast cell leukemia uncovers clues that could improve therapy

Cancer researchers at Cold Spring Harbor Laboratory (CSHL) have carried out the first comprehensive study of the changes seen in the DNA of a patient with mast cell leukemia (MCL), an extremely aggressive subtype of acute ...

Cancer created Dec 16, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Schizophrenia: Small genetic changes pose risk for disease

(Medical Xpress) -- Carrying single DNA letter changes from two different genes together may increase the risk of developing schizophrenia, Johns Hopkins researchers reported in the November 16 issue of Neuron.

Genetics created Dec 16, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Rare gene variant implicates vitamin D in cause of multiple sclerosis

(Medical Xpress) -- A rare genetic variant that appears to be directly and causally linked to multiple sclerosis (MS) has been identified by Oxford University researchers.

Neuroscience created Dec 09, 2011 | popularity 5 / 5 (6) | comments 0 | with audio podcast