Whether tall or short, a person's height increases their risk for a variety of diseases, according to a new study led by Sridharan Raghavan of the Rocky Mountain Regional VA Medical Center, U.S. publishing June 2nd in the ...
Jun 2, 2022
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A team of researchers has found a way to gauge the rate of extreme inbreeding (EI) in the U.K. and its possible health repercussions. In their paper published in the journal Nature Communications, the group describes their ...
Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the ...
Dec 21, 2021
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"Biology shows us that there are additional ways to reduce the risk of serious coronavirus infections, in addition to hand hygiene and keeping distance," Viola Vogel writes.
Mar 13, 2020
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When cells divide, through a process called mitosis, the genetic information must be equally distributed among the new cells. That is the moment when mitotic errors can arise, potentially leading to DNA damage, including ...
Jan 20, 2022
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People whose sleep pattern goes against their natural body clock are more likely to have depression and lower levels of wellbeing, according to a largescale new study.
Jun 7, 2021
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(Medical Xpress)—In the realm of DNA sequencing, the Polymerase Chain Reaction (PCR) is a well-established tool for amplifying a specific DNA sequence by reiteratively processing what's known as a reaction cocktail between ...
One of the world's largest studies on the impact of cholesterol-lowering medication has highlighted an issue with a new class of drugs that could impair lung function in some patients.
Jul 20, 2023
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Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according ...
Oct 28, 2022
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The foods we eat may have a direct impact on our cognitive acuity in our later years. This is the key finding of an Iowa State University research study spotlighted in an article published in the November 2020 issue of the ...
Dec 10, 2020
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A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.
The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."
Sequences can be derived from the biological raw material through a process called DNA sequencing.
In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:
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