News tagged with genetic model
Genetic mutation linked with typical form of migraine
A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.
Genetics
May 01, 2013 |
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Key mechanism for a common form of Alzheimer's disease discovered
Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...
Alzheimer's disease & dementia
Apr 25, 2013 |
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Immune system changes may drive aggressiveness of recurrent tumors
Nearly half of the 700,000 cancer patients who undergo surgical removal of a primary tumor each year suffer a recurrence of their disease at some point, and many of those patients will eventually die from their disease. The ...
Cancer
Dec 27, 2012 |
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Uncovering secrets of how intellect and behavior emerge during childhood
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that a single protein plays an oversized role in intellectual and behavioral development. The scientists found that mutations in a single ...
Genetics
Nov 08, 2012 |
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Gene therapy restores sense of smell, may aid research into other diseases caused by cilia defects
Scientists have restored the sense of smell in mice through gene therapy for the first time—a hopeful sign for people who can't smell anything from birth or lose it due to disease.
Medical research
Sep 02, 2012 |
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Scientists correct Huntington's disease mutation in induced pluripotent stem cells
Johns Hopkins researchers, working with an international consortium, say they have generated stem cells from skin cells from a person with a severe, early-onset form of Huntington's disease (HD), and turned them into neurons ...
Medical research
Jun 28, 2012 |
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Novel mouse model for autism yields clues to a 50-year-old mystery
Early disruptions in serotonin signaling in the brain may contribute to autism spectrum disorder (ASD), and other "enduring effects on behavior," Vanderbilt University researchers report.
Autism spectrum disorders
Mar 20, 2012 |
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Researchers identify promising new drug target for kidney disease
Researchers from Mount Sinai School of Medicine have identified a regulator protein that plays a crucial role in kidney fibrosis, a condition that leads to kidney failure. Finding this regulator provides a new therapeutic ...
Diseases, Conditions, Syndromes
Mar 11, 2012 |
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When nerve meets muscle, biglycan seals the deal
A protein that has shown early promise in preventing the loss of muscle function in mouse models of Duchenne muscular dystrophy, has been found in a new study to be a key player in the process of joining nerves ...
Neuroscience
Feb 14, 2012 |
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Researchers engineer blood stem cells to fight melanoma
Researchers from UCLA's cancer and stem cell centers have demonstrated for the first time that blood stem cells can be engineered to create cancer-killing T-cells that seek out and attack a human melanoma. The researchers ...
Cancer
Nov 28, 2011 |
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Yeast model connects Alzheimer's disease risk and amyloid beta toxicity
In a development that sheds new light on the pathology of Alzheimer's disease (AD), a team of Whitehead Institute scientists has identified connections between genetic risk factors for the disease and the ...
Medical research
Oct 27, 2011 |
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New evidence for genetic basis of autism found
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that one of the most common genetic alterations in autism -- deletion of a 27-gene cluster on chromosome 16 -- causes autism-like features. ...
Genetics
Oct 03, 2011 |
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Experts propose new unified genetic model for human disease
Based on a wide variety of genetic studies and analysis– from genome wide association studies looking for common variations in the DNA of many people with complex diseases to the sequencing of specific gene mutations ...
Genetics
Sep 29, 2011 |
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Control of fear in the brain decoded
When healthy people are faced with threatening situations, they react with a suitable behavioural response and do not descend into a state of either panic or indifference, as is the case, for example, with ...
Neuroscience
Sep 06, 2011 |
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Scientists find new drug target in breast cancer
Researchers have identified a new protein involved in the development of drug resistance in breast cancer which could be a target for new treatments, they report today in the journal Nature Medicine.
Cancer
May 22, 2011 |
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