Genetics

Study finds genetic risk of COVID-19

An analysis of the DNA of thousands of people who have been infected with the coronavirus, SARS-CoV-2, and shown a positive test for the disease it causes, COVID-19, shows that they have several DNA characteristics in common. ...

Alzheimer's disease & dementia

Insights on the link between chronic stress and Alzheimer's disease

Chronic psychosocial stress—which involves a pathway called the hypothalamic-pituitary-adrenal axis (HPA axis)—may contribute to the development of Alzheimer's disease. A new review published in Biological Reviews describes ...

Oncology & Cancer

Predicting resistance to anticancer drugs

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails. Understanding this 'choice' by the cancer cells may ...

Oncology & Cancer

Researchers identify genes behind uterine leiomyosarcoma

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS). Furthermore, using fully sequenced patient-derived xenografts, the team has preclinically validated new ...

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