Neuroscience

Zebrafish brain repair following concussion

A simple and inexpensive zebrafish model of concussion, reported in eNeuro, reveals the genetic pathways underlying the animal's remarkable ability to regenerate injured brain tissue. Understanding the mechanisms of regeneration ...

Oncology & Cancer

Atoh1, a potential Achilles' heel of Sonic Hedgehog medulloblastoma

Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side effects, including psychiatric disorders, growth retardation ...

Cardiology

Raising 'good' cholesterol fails to protect against heart disease

Raising so-called 'good' cholesterol by blocking a key protein involved in its metabolism does not protect against heart disease or stroke, according to a large genetic study of 150,000 Chinese adults published in the journal ...

Genetics

Diabetes and heart disease linked by genes, study reveals

Type 2 diabetes (T2D) has become a global epidemic affecting more than 380 million people worldwide; yet there are knowledge gaps in understanding the etiology of type-2 diabetes. T2D is also a significant risk factor for ...

Oncology & Cancer

Scientists uncover potential mechanism for HPV-induced skin cancer

Scientists have identified a molecular pathway by which some types of human papilloma virus (HPV) might increase the risk of skin cancer, particularly in people with the rare genetic disorder epidermodysplasia verruciformis ...

Oncology & Cancer

Newly discovered cellular pathway may lead to cancer therapies

Scientists have discovered a new cellular pathway that can promote and support the growth of cancer cells. In a mouse model of melanoma, blocking this pathway resulted in reduction of tumor growth. The study, which appears ...

Oncology & Cancer

Tracking cancer's signaling pathways

Malignant melanoma is one of the most common and dangerous types of cancer. Researchers at Friedrich-Alexander Universität Erlangen-Nürnberg (FAU) investigated how and why brown pigmented moles turn into malignant melanoma ...

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