News tagged with genetic pathways


Researchers discover gene that permanently stops cancer cell proliferation

Researchers at Case Western Reserve University School of Medicine have discovered a mutant form of the gene, Chk1, that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without ...

Cancer created Aug 01, 2012 | popularity 4.9 / 5 (49) | comments 7 | with audio podcast

Of enzymes and aging: Tryptophan metabolism plays key role in aging and age-related neurological diseases

(Medical Xpress)—In the battle against aging and age-related neurological diseases such as Parkinson's and Alzheimer's, a key factor has long appeared to be the toxicity of proteins which tend to aggregate. ...

Medical research created Oct 05, 2012 | popularity 4.7 / 5 (14) | comments 3 | with audio podcast feature

Scientists discover switch that turns white fat brown

Scientists have discovered a biological switch that gives energy-storing white fat the characteristics of energy-burning brown fat. The findings could lead to new strategies for treating obesity.

Medical research created Sep 06, 2011 | popularity 5 / 5 (5) | comments 0 | with audio podcast

A new approach to faster anticancer drug discovery

Tracking the genetic pathway of a disease offers a powerful, new approach to drug discovery, according to scientists at the University of California, San Diego School of Medicine who used the approach to uncover a potential ...

Cancer created Mar 13, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

First gene linked to common form of psoriasis identified

Scientists led by Washington University School of Medicine in St. Louis have identified the first gene directly linked to the most common form of psoriasis, a chronic skin condition.

Genetics created Apr 19, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Key mechanism for a common form of Alzheimer's disease discovered

Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...

Alzheimer's disease & dementia created Apr 25, 2013 | popularity 4.6 / 5 (5) | comments 0 | with audio podcast

Scientists find potential loophole in pancreatic cancer defenses

Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control ...

Cancer created Mar 27, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Study finds new genetic cause of neurodegeneration

(Medical Xpress) -- Mayo Clinic researchers have discovered two mutations responsible for a devastating neurological condition they first identified 15 years ago. The researchers say their study -- appearing in Nature Ge ...

Genetics created May 01, 2011 | popularity 4.3 / 5 (4) | comments 0 | with audio podcast

New ADHD findings

A combination of rare and common genetic variations could play a part in biological pathways linked to Attention Deficit Hyperactivity Disorder (ADHD).

Attention deficit disorders created Nov 14, 2011 | popularity 5 / 5 (3) | comments 0

Genome-wide scan maps mutations in deadly lung cancers; reveals embryonic gene link

Scientists have completed a comprehensive map of genetic mutations linked to an aggressive and lethal type of lung cancer.

Genetics created Sep 05, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers identify key genes and prototype predictive test for schizophrenia

An Indiana University-led research team, along with a group of national and international collaborators, has identified and prioritized a comprehensive group of genes most associated with schizophrenia that together can generate ...

Genetics created May 15, 2012 | popularity 4.7 / 5 (3) | comments 1 | with audio podcast

Study identifies 75 genetic regions that influence red blood cell formation

New research is revealing how red blood cells are made and how the body regulates the amount of haemoglobin that is packaged in red blood cells at any time. Genomic analysis techniques have doubled the number of genetic regions ...

Genetics created Dec 05, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

New approach to link genome-wide association signals to biological function

Researchers have developed a new strategy to improve the outcome of genome-wide association (GWA) studies.

Genetics created Jun 30, 2011 | popularity 5 / 5 (2) | comments 0

Study identifies genetic basis of human metabolic individuality

In what is so far the largest investigation of its kind, researchers uncovered a wide range of new insights about common diseases and how they are affected by differences between two persons' genes. The results from this ...

Genetics created Oct 26, 2011 | popularity 3.3 / 5 (3) | comments 0 | with audio podcast

Unlocking the genetic and molecular mystery of soft-tissue sarcoma

Scientists at Joslin Diabetes Center in Boston have uncovered important molecular and genetic keys to the development of soft-tissue sarcomas in skeletal muscle, giving researchers and clinicians additional targets to stop ...

Cancer created Nov 30, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast