News tagged with genetic pathways


Of enzymes and aging: Tryptophan metabolism plays key role in aging and age-related neurological diseases

(Medical Xpress)—In the battle against aging and age-related neurological diseases such as Parkinson's and Alzheimer's, a key factor has long appeared to be the toxicity of proteins which tend to aggregate. ...

Medical research created Oct 05, 2012 | popularity 4.7 / 5 (14) | comments 3 | with audio podcast feature

Key mechanism for a common form of Alzheimer's disease discovered

Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...

Alzheimer's disease & dementia created Apr 25, 2013 | popularity 4.6 / 5 (5) | comments 0 | with audio podcast

Large-scale genetic study defines relationship between primary sclerosing cholangitis and other autoimmune diseases

For the first time, scientists show that a leading cause of liver transplant, primary sclerosing cholangitis (PSC), is a distinct disease from inflammatory bowel disease, opening up new avenues for specific PSC treatments.

Genetics created Apr 21, 2013 | popularity not rated yet | comments 0 | with audio podcast

Genetic markers ID second Alzheimer's pathway

Researchers at Washington University School of Medicine in St. Louis have identified a new set of genetic markers for Alzheimer's that point to a second pathway through which the disease develops.

Alzheimer's disease & dementia created Apr 04, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Mouse study offers clues to obesity-diabetes link

(HealthDay)—Obesity and type 2 diabetes are clearly intertwined, but researchers say they've found a way to weaken the connection between the two—at least in mice.

Medical research created Dec 06, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study identifies 75 genetic regions that influence red blood cell formation

New research is revealing how red blood cells are made and how the body regulates the amount of haemoglobin that is packaged in red blood cells at any time. Genomic analysis techniques have doubled the number of genetic regions ...

Genetics created Dec 05, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

International study points to inflammation as a cause of plaque buildup in heart vessels

Fifteen new genetic regions associated with coronary artery disease have been identified by a large, international consortium of scientists—including researchers at the Stanford University School of Medicine—taking a ...

Genetics created Dec 02, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Genome-wide scan maps mutations in deadly lung cancers; reveals embryonic gene link

Scientists have completed a comprehensive map of genetic mutations linked to an aggressive and lethal type of lung cancer.

Genetics created Sep 05, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Scientists identify new gene that influences survival in amyotrophic lateral sclerosis

A team of scientists, including faculty at the University of Massachusetts Medical School (UMMS), have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). ...

Genetics created Aug 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

BIM gene variation in East Asians found to explain resistance to cancer drugs

A multi-national research team led by scientists at Duke-NUS Graduate Medical School has identified the reason why some patients fail to respond to some of the most successful cancer drugs.

Cancer created Mar 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

Gene research sheds light on timing of menopause

(Medical Xpress) -- An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause.

Genetics created Jan 23, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study finds new genetic cause of neurodegeneration

(Medical Xpress) -- Mayo Clinic researchers have discovered two mutations responsible for a devastating neurological condition they first identified 15 years ago. The researchers say their study -- appearing in Nature Ge ...

Genetics created May 01, 2011 | popularity 4.3 / 5 (4) | comments 0 | with audio podcast

Deficiency in p53 anti-tumor protein delays DNA repair after radiation

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...

Cancer created Apr 23, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Breast cancer researchers find new drug target companion prognostic test for hormone therapy resistance

A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...

Cancer created Apr 01, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists tie dietary influences to changes in gene expression and physiology

Sometimes you just can't resist a tiny piece of chocolate cake. Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research by scientists at the University of Massachusetts ...

Medical research created Mar 28, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast