News tagged with genetic profiles
First prospective trial shows molecular profiling timely for tailoring therapy
A clinical trial has shown that patients, and their physicians, are eager to jump into next-era cancer care—analysis of an individual's tumor to find and target genetic mutations that drive the cancer. Results of the study, ...
Cancer
May 15, 2013 |
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Genetic variations associated with susceptibility to bacteria linked to stomach disorders
Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and st ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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Breast cancer heterogeneity no barrier to predictive testing, study shows
Breast cancers contain many different cell types with different patterns of gene expression, but a new study provides reassurance that this variability should not be a barrier to using gene expression tests to help tailor ...
Cancer
May 02, 2013 |
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Scientists assemble genetic playbook for acute leukemia
A team of researchers led by Washington University School of Medicine in St. Louis has identified virtually all of the major mutations that drive acute myeloid leukemia (AML), a fast-growing blood cancer ...
Cancer
May 01, 2013 |
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Computer algorithms help find cancer connections
Powerful data-sifting algorithms developed by computer scientists at Brown University are helping to untangle the profoundly complex genetics of cancer. In a study reported today in the New England Journal of Medicine, resear ...
Cancer
May 01, 2013 |
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Virus-like particles provide vital clues about brain tumors
Exosomes are small, virus-like particles that can transport genetic material and signal substances between cells. Researchers at Lund University, Sweden, have made new findings about exosomes released from aggressive brain ...
Medical research
Apr 17, 2013 |
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K9 osteosarcoma samples identify drivers of metastasis in pediatric bone cancer
Human osteosarcoma samples are hard to come by, making the disease difficult to study. However, K9 bone cancer is genetically indistinguishable from the human form of the disease, and over 10,000 canine patients develop the ...
Cancer
Apr 09, 2013 |
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Legal levels of atrazine alter neuroendocrine, reproductive genes in zebrafish
(Medical Xpress)—A Purdue University study found an agricultural herbicide alters reproductive and neuroendocrine genes during embryonic development in fish, a finding that will help establish a genetic ...
Medical research
Apr 03, 2013 |
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Genetics might determine which smokers get hooked, research says
Researchers have identified genetic risk factors that may accelerate a teen's progression to becoming a lifelong heavy smoker.
Psychology & Psychiatry
Mar 27, 2013 |
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Ganetespib shows potency against ALK-positive lung cancer and overcomes crizotinib resistance
A drug that indirectly impairs the function of several cancer-driving proteins, including anaplastic lymphoma kinase (ALK), may be an effective new treatment for patients with ALK—positive non-small cell lung cancer.
Cancer
Mar 26, 2013 |
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Blood test might help guide pancreatic cancer treatment
(HealthDay)—A simple blood test might help predict a pancreatic cancer patient's chances of benefiting from chemotherapy, a small study suggests.
Cancer
Jan 23, 2013 |
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New test predicted presence of harmful BRCA mutations
A new multiple gene expression profile test was able to predict the presence of harmful BRCA1 or BRCA2 mutations in otherwise healthy women carrying the mutations, according to data published in Cancer Prevention Research, a jour ...
Cancer
Jan 22, 2013 |
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Tumors evolve rapidly in a childhood cancer, leaving fewer obvious tumor targets
An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene ...
Genetics
Jan 20, 2013 |
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Valuable tool for predicting pain genes in people
Scientists in Australia and Austria have described a "network map" of genes involved in pain perception. The work, published in the journal PLOS Genetics should help identify new analgesic drugs.
Genetics
Dec 06, 2012 |
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TGen-US Oncology data guides treatment of metastatic triple-negative breast cancer patients
Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) ...
Cancer
Dec 06, 2012 |
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