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Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging

(Medical Xpress)—Like finally seeing all the gears of a watch and how they work together, researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components ...

Medical research created Apr 12, 2013 | popularity 5 / 5 (15) | comments 2 | with audio podcast

The compound in the Mediterranean diet that makes cancer cells 'mortal'

New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...

Cancer created 18 hours ago | popularity 4.8 / 5 (13) | comments 3 | with audio podcast

Potential diabetes breakthrough: Researchers discover new hormone spurring beta cell production

Researchers at the Harvard Stem Cell Institute (HSCI) have discovered a hormone that holds promise for a dramatically more effective treatment of type 2 diabetes, a metabolic illness afflicting an estimated ...

Medical research created Apr 25, 2013 | popularity 4.9 / 5 (12) | comments 0 | with audio podcast

Researchers abuzz over caffeine as cancer-cell killer

(Medical Xpress)—Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells—results that could one day ...

Cancer created Apr 18, 2013 | popularity 4.6 / 5 (11) | comments 0 | with audio podcast

Final chapter to 60-year-old blood group mystery

Researchers have solved a 60-year-old mystery by identifying a gene that can cause rejection, kidney failure and even death in some blood transfusion patients. In this study, published in Nature Genetics online ...

Genetics created Apr 07, 2013 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Reversing paralysis with restorative gel: Researchers develop implant to regenerate nerves

(Medical Xpress)—Some parts of the body, like the liver, can regenerate themselves after damage. But others, such as our nervous system, are considered either irreparable or slow to recover, leaving thousands ...

Neuroscience created May 13, 2013 | popularity 5 / 5 (8) | comments 1 | with audio podcast

New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice

(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...

Cancer created May 08, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Ebola's secret weapon revealed

Researchers have discovered the mechanism behind one of the Ebola virus' most dangerous attributes: its ability to disarm the adaptive immune system.

Medical research created May 02, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Key mechanism for a common form of Alzheimer's disease discovered

Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...

Alzheimer's disease & dementia created Apr 25, 2013 | popularity 4.6 / 5 (5) | comments 0 | with audio podcast

Mitochondrial metabolic regulator SIRT4 guards against DNA damage

(Medical Xpress)—Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.

Cancer created Apr 05, 2013 | popularity 5 / 5 (4) | comments 2 | with audio podcast

Turning back the clock on regeneration in neurons

(Medical Xpress)—When minor wounds heal, the fine nerve endings that sense touch, or control sweating, are usually able to regrow. Like many processes in the body, the ability to regenerate new tissues ...

Neuroscience created Apr 19, 2013 | popularity 5 / 5 (4) | comments 2 | with audio podcast report

Researchers identify new potential target for cancer therapy

Researchers at UT Southwestern Medical Center have found that alternative splicing – a process that allows a single gene to code for multiple proteins – appears to be a new potential target for anti-telomerase ...

Cancer created Apr 19, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Telomere shortening affects muscular dystrophy gene

(Medical Xpress)—Facioscapulohumeral muscular dystrophy (FSHD) is a genetic disorder that causes the muscles of the upper body to waste away. It is unusual in that symptoms do not usually appear until sufferers are in their ...

Genetics created May 06, 2013 | popularity 4.8 / 5 (4) | comments 3 | with audio podcast report

Serotonin mediates exercise-induced generation of new neurons

Mice that exercise in running wheels exhibit increased neurogenesis in the brain. Crucial to this process is serotonin signaling. These are the findings of a study by researchers at the Max Delbrück Center ...

Neuroscience created May 13, 2013 | popularity 4.8 / 5 (4) | comments 0

Autism linked to increased genetic change in regions of genome instability

(Medical Xpress)—Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery to be published ...

Autism spectrum disorders created Apr 03, 2013 | popularity 3.6 / 5 (5) | comments 0 | with audio podcast

Genetics

Genetics (from Ancient Greek γενετικός genetikos, “genitive” and that from γένεσις genesis, “origin”), a discipline of biology, is the science of heredity and variation in living organisms. The fact that living things inherit traits from their parents has been used since prehistoric times to improve crop plants and animals through selective breeding. However, the modern science of genetics, which seeks to understand the process of inheritance, only began with the work of Gregor Mendel in the mid-nineteenth century. Although he did not know the physical basis for heredity, Mendel observed that organisms inherit traits via discrete units of inheritance, which are now called genes.

Genes correspond to regions within DNA, a molecule composed of a chain of four different types of nucleotides—the sequence of these nucleotides is the genetic information organisms inherit. DNA naturally occurs in a double stranded form, with nucleotides on each strand complementary to each other. Each strand can act as a template for creating a new partner strand—this is the physical method for making copies of genes that can be inherited.

The sequence of nucleotides in a gene is translated by cells to produce a chain of amino acids, creating proteins—the order of amino acids in a protein corresponds to the order of nucleotides in the gene. This relationship between nucleotide sequence and amino acid sequence is known as the genetic code. The amino acids in a protein determine how it folds into a three-dimensional shape; this structure is, in turn, responsible for the protein's function. Proteins carry out almost all the functions needed for cells to live. A change to the DNA in a gene can change a protein's amino acids, changing its shape and function: this can have a dramatic effect in the cell and on the organism as a whole. Two additional factors that can change the shape of the protein are pH and temperature.

Although genetics plays a large role in the appearance and behavior of organisms, it is the combination of genetics with what an organism experiences that determines the ultimate outcome. For example, while genes play a role in determining an organism's size, the nutrition and other conditions it experiences after inception also have a large effect.

For more information about Genetics, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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