Researchers at the University of Toronto's Donnelly Center for Cellular and Biomolecular Research have found nearly one million new exons—stretches of DNA that are expressed in mature RNA—in the human genome.
Feb 9, 2024
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While combing through the human genome in 2007, computational geneticist Pardis Sabeti made a discovery that would transform her research career. As a then-postdoctoral fellow at the Broad Institute of MIT and Harvard, Sabeti ...
Feb 8, 2024
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Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly ...
Feb 7, 2024
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In a recent study, investigators from Rockefeller University and other institutions have discovered a never-before-documented genetic disorder that causes the improper functioning of macrophages.
Feb 6, 2024
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Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are ...
Feb 6, 2024
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A multinational team of researchers led by Columbia University has discovered that tumors can repurpose a single cellular protein to hide themselves from the immune system in two distinct ways. Drugs targeting that protein ...
Feb 2, 2024
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Angioedema is a rare but potentially life-threatening adverse reaction to ACE inhibitors. In a joint analysis of eight European study collectives, researchers from the University Hospital Bonn (UKB), the University of Bonn ...
Jan 31, 2024
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A team of researchers at the Carl Gustav Carus Faculty of Medicine, University of Technology Dresden, led by Prof. Frank Buchholz, has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge ...
Jan 31, 2024
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Whether we stay healthy or become seriously ill is determined by our genes. But also, the folding of our genome has a significant influence on this, as the 3D genome organization regulates which genes are switched on and ...
Jan 30, 2024
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While it is well established that chromosomal abnormalities are a major cause of miscarriages the biology behind pregnancy losses with or without chromosomal errors is not well understood. Over 114 thousand women from Iceland, ...
Jan 29, 2024
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