News tagged with genomic analysis


Mouse study provides new clue to staying skinny on a high-fat diet

(Medical Xpress)—The mystery of why some people get fat eating high-fat foods while others can stay skinny on a diet of burgers and chips is closer to being solved.

Diabetes created May 01, 2013 | popularity 3 / 5 (2) | comments 1

Securely storing and interpreting the genome

At a time when sequencing the genome is becoming democratized, questions have arisen about the interpretation of these data and their secure storage. Sophia Genetics, an EPFL Science Park start-up, specializes in this. The ...

Genetics created Apr 19, 2013 | popularity not rated yet | comments 0

Completion of the zebrafish reference genome yields strong comparisons with the human genome

Researchers demonstrate today that 70 per cent of protein-coding human genes are related to genes found in the zebrafish and that 84 per cent of genes known to be associated with human disease have a zebrafish counterpart. ...

Genetics created Apr 17, 2013 | popularity not rated yet | comments 0 | with audio podcast

Exploring lincRNA's role in breast cancer

Once considered part of the "junk" of our genome, much of the DNA between protein-coding genes is now known to be transcribed. New findings by scientists at Fox Chase Cancer Center have identified several dozen transcripts ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Comprehensive genomic analysis identifies alterations in head and neck cancer that could lead to targeted therapy

Not all head and neck squamous cell carcinomas (HNSCCs) have the same pattern of genomic alterations, but those cancers with certain distinctive patterns could be amenable to specific targeted therapies, according to a researcher ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Counting copy numbers characterises prostate cancer

Non-invasive 'liquid biopsies' can find metastatic or recurrent prostate cancer, in a low cost assay suitable for most healthcare systems, finds research published in BioMed Central's open access journal Genome Medicine. Genomi ...

Cancer created Apr 04, 2013 | popularity not rated yet | comments 0

LoFreq: Ultrafast detection of microbe and cancer cell mutations

Scientists at A*STAR's Genome Institute of Singapore (GIS) have developed a novel technique to precisely monitor and study the evolution of micro-organisms such as viruses and bacteria. This is an extremely important capability ...

Medical research created Mar 07, 2013 | popularity not rated yet | comments 0

For some, surgical site infections are in the genes

(Medical Xpress)—An estimated 300,000 U.S. patients get surgical site infections every year, and while the causes are varied, a new University of Utah study suggests that some who get an infection can blame ...

Surgery created Feb 26, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers find multiple tests needed to detect infection in low birth-weight newborns

New research by Case Western Reserve University School of Dental Medicine and Yale University School of Medicine finds that cultures commonly used to detect bacterial infections in low birth-weight newborns with early onset ...

Pediatrics created Feb 20, 2013 | popularity not rated yet | comments 0

Personal epigenetic 'signatures' found consistent in prostate cancer patients' metastases

In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...

Cancer created Jan 23, 2013 | popularity not rated yet | comments 0 | with audio podcast

Unmasking the deadly secrets of pancreatic cancer

(Medical Xpress)—A large-scale study that defines the complexity of underlying mutations responsible for pancreatic cancers in more than 100 patients was published in Nature.

Cancer created Oct 25, 2012 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Genome analysis of pancreas tumors reveals new pathway

The latest genomic analysis of pancreatic tumors identified two new pathways involved in the disease, information that could be capitalized on to develop new and earlier diagnostic tests for the disease

Cancer created Oct 24, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

AMP reports on possibilities, challenges, and applications of next-generation sequencing

Bethesda, MD, October 18, 2012 The Association for Molecular Pathology (AMP) published the report of the Whole Genome Analysis (WGA) Working Group of the AMP Clinical Practice Committee in the November 2012 issue of The Journal of ...

Genetics created Oct 18, 2012 | popularity not rated yet | comments 0

First large scale trial of whole-genome cancer testing for clinical decision-making reported

For the first time, researchers have conducted a large trial in which they tested the entire genome of individual breast cancers to help personalize treatment. They released their findings at the ESMO 2012 Congress of the ...

Cancer created Oct 01, 2012 | popularity not rated yet | comments 0

Informatics approach helps doctors, patients make sense of genome data

The cost of sequencing the entire human genome, or exome – the regions of the genome that are translated into proteins that affect cell behavior – has decreased significantly, to the point where the cost of looking at ...

Genetics created Sep 20, 2012 | popularity not rated yet | comments 0 | with audio podcast