Cardiology

Genotype doesn't predict A-fib in hypertrophic cardiomyopathy

(HealthDay)—For patients with hypertrophic cardiomyopathy (HC), genotype does not predict onset or severity of atrial fibrillation (AF), according to a study published in the April 1 issue of The American Journal of Cardiology.

Diabetes

CYP2C19 polymorphisms impacts citalopram metabolism

(HealthDay)—For patients with major depressive disorder, certain CYP2C19 polymorphisms contribute to citalopram (CIT) metabolism, according to research published in the December issue of the Journal of Clinical Pharmacy ...

Diseases, Conditions, Syndromes

AFP levels predict fibrosis regression after SVR in hep C

(HealthDay)—For patients with chronic hepatitis C virus (HCV), lower post-treatment α-fetoprotein (AFP) levels and HCV genotype 2 correlate with liver fibrosis regression after sustained virological response (SVR), according ...

Diseases, Conditions, Syndromes

Sofosbuvir-velpatasvir successful in hep C regardless of genotype

(HealthDay)—Sofosbuvir-velpatasvir is effective for hepatitis C virus (HCV), regardless of genotype, according to three studies published online Nov. 17 in the New England Journal of Medicine. The research was published ...

Oncology & Cancer

ERCC1 SNP can identify good prognosis in nasopharyngeal CA

(HealthDay)—Excision repair cross-complementing group 1 (ERCC1) genotype for the single nucleotide polymorphism (SNP) cytosine-to-thymine substitution at codon 118 (C118T) interacts with post-radiotherapy plasma Epstein-Barr ...

Diseases, Conditions, Syndromes

Technivie approved for hepatitis C

(HealthDay)—Technivie (ombitasvir, paritaprevir and ritonavir) has been approved by the U.S. Food and Drug Administration, in tandem with ribavirin, to treat hepatitis C genotype 4 infection among people without poor liver ...

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