An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen ...
Feb 1, 2018
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For the first time, scientists show that a leading cause of liver transplant, primary sclerosing cholangitis (PSC), is a distinct disease from inflammatory bowel disease, opening up new avenues for specific PSC treatments.
Apr 21, 2013
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Long-term use of high-dose green tea extract may provide some protection against cancer, cardiovascular disease, obesity and type 2 diabetes, but it also may create liver damage in a small minority of the population.
Dec 1, 2022
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(HealthDay)—Age, sex and apolipoprotein E (APOE) genotype can identify groups at high 10-year risk for Alzheimer's disease and all dementia, according to a study published Sept. 4 in CMAJ, the journal of the Canadian Medical ...
Sep 21, 2018
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A new study shows that having a high amount of beta amyloid or "plaques" in the brain associated with Alzheimer's disease may cause steeper memory decline in mentally healthy older people than does having the APOE ɛ4 allele, ...
Oct 15, 2012
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The fixed-dose drug combination ombitasvir/paritaprevir/ritonavir (trade name Viekirax) has been available since January 2015 for the treatment of adults with chronic hepatitis C infection. The German Institute for Quality ...
May 28, 2015
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(HealthDay)—Antisocial behavior (ASB) may be highly polygenic, with sex-discordant associations identified for some loci, according to a study published online Oct. 4 in JAMA Psychiatry.
Oct 9, 2017
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A new combination of investigational drugs successfully suppressed hepatitis C genotype 1 infection in a high percent of patients who had not responded to previous treatment in a study led by a University of Michigan hepatologist.
Jan 19, 2012
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US biotech firm Gilead Sciences announced plans Monday to acquire rival Pharmasset, a group specializing in treatments for AIDS and hepatitis, for $11 billion.
Nov 21, 2011
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Are female carriers of the apolipoprotein E ?4 allele, the main genetic risk factor for late-onset Alzheimer disease, at greater risk of developing the disease than men? A new article published by JAMA Neurology examines ...
Aug 28, 2017
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