Recent technological advances have revolutionised our ability to manipulate the genetic code, allowing us to specifically edit individual genes. Gene editing offers exciting potential for disease therapies but application ...
Dec 2, 2015
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Research carried out by Francis Crick Institute scientists provides new insights into sex chromosome disorders which typically cause infertility, such as Turner syndrome and Klinefelter syndrome. Through their research, the ...
Jan 27, 2017
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In a study of nearly 9,000 people treated for solid tumor cancers, researchers found that radiation treatment and tobacco use were linked to higher rates of blood-based DNA mutations that could lead to higher risk for blood ...
Aug 14, 2017
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Male fetuses of mothers that are exposed to radiation during early pregnancy may have an increased chance of developing testicular cancer, according to a study in mice at The University of Texas MD Anderson Cancer Center. ...
Feb 13, 2012
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Scientists have discovered that some treatments for cancer and sickle cell disease can destroy the germ cells that go on to develop into sperm in the testes of young boys. In some pre-pubescent boys, the treatment for sickle ...
Jul 24, 2018
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Germ cells have unique molecular features that enable them to perform the important task of transmitting genetic information to the next generation. During development from their embryonic primordial state, germ cells are ...
Aug 23, 2013
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Recently published work from Carnegie's Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step as they mature into functionality. Their findings ...
Oct 8, 2020
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Scientists at Indiana University and colleagues at Stanford and the University of Texas have demonstrated a technique for "editing" the genome in sperm-producing adult stem cells, a result with powerful potential for basic ...
Dec 15, 2014
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(HealthDay)—In germ cell tumors (GCTs), TP53 and MDM2 alterations correlate with cisplatin resistance and are associated with inferior outcome, according to a study published online Sept. 19 in the Journal of Clinical Oncology.
Sep 23, 2016
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In a new paper released today in Nature, BioFrontiers Institute scientists at the University of Colorado Boulder, Tom Cech and Leslie Leinwand, detailed a new target for anti-cancer drug development that is sitting at the ...
Oct 24, 2012
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