Modification of tumor suppressor affects sensitivity to potential GBM treatment
Despite years of research, glioblastoma, the most common and deadly brain cancer in adults, continues to outsmart treatments targeted to inhibit tumor growth.
Cancer
Aug 13, 2012 |
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Study pinpoints a genetic cause of most lethal brain tumor, may lead to new treatment
Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent ...
Cancer
Jul 26, 2012 |
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Researchers study vaccine as potential weapon against aggressive brain tumors
Researchers at Northwestern Brain Tumor Institute (NBTI) are seeking to understand if a vaccine made from a patient's own blood cells may slow the growth of a type of brain tumor. The trial is studying the vaccine's effect ...
Cancer
Jul 24, 2012 |
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Better treatment for brain cancer revealed by new molecular insights
Nearly a third of adults with the most common type of brain cancer develop recurrent, invasive tumors after being treated with a drug called bevacizumab. The molecular underpinnings behind these detrimental effects have now ...
Cancer
Jul 09, 2012 |
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Probability of long-term glioblastoma survival assessed
(HealthDay) -- Although the overall mortality rate of glioblastoma is high, compared with patients newly diagnosed with glioblastoma, those who survive two years or more after diagnosis have a favorable conditional ...
Cancer
May 28, 2012 |
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Revised glioblastoma classification should improve patient care
Radiation oncology researchers have revised the system used by doctors since the 1990s to determine the prognosis of people with glioblastoma, which is the most devastating of malignant brain tumors.
Cancer
May 16, 2012 |
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Brain cancer vaccine proves effective
A new brain cancer vaccine tailored to individual patients by using material from their own tumors has proven effective in a multicenter phase 2 clinical trial at extending their lives by several months or longer. The patients ...
Cancer
Apr 17, 2012 |
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A culprit behind brain tumor resistance to therapy
Persistent protein expression may explain why tumors return after therapy in glioblastoma patients, according to a study published on March 5th in the Journal of Experimental Medicine.
Cancer
Mar 05, 2012 |
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Genetic breakthrough for brain cancer in children
An international research team led by the Research Institute of the McGill University Health Centre (RI MUHC) has made a major genetic breakthrough that could change the way pediatric cancers are treated in the future. The ...
Cancer
Jan 30, 2012 |
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Possible new pathway can overcome glioblastoma resistance
Glioblastoma, a lethal brain cancer, is one of the most resistant to available therapies and patients typically live approximately 15 months.
Cancer
Jan 24, 2012 |
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Scientists uncover novel mechanism of glioblastoma development
Most research on glioblastoma development, a complicated tumor of the brain with a poor prognosis, has focused on the gene transcription level, but scientists suggest that post-transcriptional regulation could be equally ...
Cancer
Jan 18, 2012 |
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Personalized gene therapies may increase survival in brain cancer patients
Personalized prognostic tools and gene-based therapies may improve the survival and quality of life of patients suffering from glioblastoma, an aggressive and deadly form of brain cancer, reports a new University of Illinois ...
Cancer
Jan 09, 2012 |
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Study finds amplification of multiple cell-growth genes in some brain tumors
A small percentage of the deadly brain tumors called glioblastomas, which usually resist treatment with drugs targeting mutations in cell-growth genes, appears to contain extra copies of two or three of these genes at the ...
Cancer
Dec 01, 2011 |
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Glioblastoma multiforme in the Dock
Glioblastoma multiforme (GBM) is the most common malignant brain cancer in humans. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. ...
Cancer
Nov 14, 2011 |
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Researchers find coupling of proteins promotes glioblastoma development
Two previously unassociated proteins known to be overly active in a variety of cancers bind together to ignite and sustain malignant brain tumors, a research team led by scientists at The University of Texas MD Anderson Cancer ...
Cancer
Oct 21, 2011 |
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