A combination of two targeted cancer drugs showed unprecedented, "clinically meaningful" activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by ...
Nov 25, 2021
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Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain ...
Nov 15, 2021
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A common mutation in gliomas sensitizes them to immunotherapy, a finding that researchers believe could have broader therapeutic implications for all glioma patients.
Sep 29, 2021
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Gliomas are the most common primary brain tumors in adults. Among them, the high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease ...
Sep 16, 2021
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Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of multiple oncogenes in glioma cells, mechanisms that promote overall glioma tumor growth and resistance to therapy, ...
Aug 26, 2021
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A novel therapy engineered by Northwestern Medicine investigators improved progression-free and overall survival for patients with newly diagnosed malignant gliomas, according to results from a recent phase I clinical trial ...
Jul 30, 2021
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Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim and Freiburg ...
May 24, 2021
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Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects ...
Apr 19, 2021
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Glioma is a fatal neurological disorder that has limited interventional treatment, despite extensive research over the past several decades. A research team led by Dr. Gong Chen, a former professor at Penn State University ...
Mar 23, 2021
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A research team from both Scottish and UK institutions using infrared spectroscopy at Diamond Light Source reports a major advance in brain tumor diagnosis made by. This will enable non-invasive diagnoses of primary brain ...
Feb 3, 2021
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