Many Americans think of gout as a disease from a bygone era, akin to rickets or scurvy. The condition commonly afflicted the rich and royal, including American historical figures such as Benjamin Franklin and Thomas Jefferson.
Dec 13, 2022
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Gout is an inflammatory disease that can cause very painful attacks. The illness is also called podagral, or colloquially "The Captain's syndrome". It primarily affects men, particularly over 40 years of age. Symptoms of ...
Mar 21, 2019
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New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome. The study will be presented today at the American Physiological ...
Oct 4, 2019
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By combining two medications, researchers at Michigan Medicine optimized a therapy for people with gout, a condition that causes severe damage and disability if left untreated.
May 11, 2021
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Affecting more than 7 million adults in the United States, gout is characterized by a sudden onset of pain, swelling and stiffness in the joints and caused by the formation of urate crystal in small spaces between joints ...
Jan 27, 2020
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University of Otago researchers have helped characterise a genetic variant that enables new understanding of why some people are at risk of gout, a painful and debilitating arthritic disease.
Sep 12, 2018
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Dietary factors have a far smaller influence on urate levels (a precursor to gout) than previously envisaged, new University of Otago research reveals.
Oct 11, 2018
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Gout is the most common cause of inflammatory arthritis and affects an estimated 20,000 people in Edinburgh alone.
Apr 19, 2022
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A history of gout is associated with an increased risk for benign paroxysmal positional vertigo (BPPV) and Meniere disease, according to a study published online Dec. 26 in the Journal of Clinical Medicine.
Feb 24, 2023
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(HealthDay)—The antihypertensive medication amlodipine is associated with a lower risk for gout compared with other antihypertensive agents, according to a study published online Jan. 20 in the Journal of Hypertension.
Feb 18, 2020
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Gout (also known as podagra when it involves the big toe) is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis—a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected (approximately 50% of cases). However, it may also present as tophi, kidney stones, or urate nephropathy. It is caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.
Diagnosis is confirmed clinically by the visualization of the characteristic crystals in joint fluid. Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, or colchicine improves symptoms. Once the acute attack has subsided, levels of uric acid are usually lowered via lifestyle changes, and in those with frequent attacks allopurinol or probenecid provide long-term prevention.
Gout has increased in frequency in recent decades affecting approximately one to two percent of the Western population at some point in their lives. The increase is believed to be due to increasing risk factors in the population, such as metabolic syndrome, longer life expectancy and changes in diet. Gout was historically known as "the disease of kings" or "rich man's disease".
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