Corneal transplantation is one of the most common human organ transplantations worldwide. Although the 1-year survival rate is as high as 90%, more than half of transplantation patients suffer various types of corneal rejection, ...
Sep 14, 2018
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When it comes to transplant rejection, some organs are far trickier than others. Some transplantable organs, such as the liver, are readily accepted by the recipient's immune system, rarely triggering an immune response and ...
Sep 6, 2018
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An international team led by researchers from the University of Pittsburgh School of Medicine found that targeting certain donor cells lowered the risk of organ rejection in mice that underwent kidney and heart transplants. ...
Aug 24, 2016
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A new study of the immunosuppressive treatment routinely used to prevent graft rejection in rats that serve as test subjects for human stem cell therapies to combat retinal degeneration has linked the immunosuppressive regimen ...
Jul 26, 2016
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A limitation of organ transplant is acute rejection of the graft by the host immune system. Graft rejection is mediated by the development of CD8+ cytotoxic T cells that target donor MHC class I molecules, and in animal models, ...
Jan 21, 2016
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Researchers in the Center for Cell and Gene Therapy at Baylor College of Medicine, Houston Methodist and Texas Children's Hospital have found that a single dose of an otherwise harmless drug can safely control the severe ...
May 14, 2015
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A research team bringing together José Cohen and Philippe Grimbert (Inserm Unit 955/Université Paris Est Créteil [UPEC] and the Centre for Clinical Investigation – Biotherapies 504 [CIC-BT 504]), and their collaborators ...
Nov 18, 2014
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In the largest study of its kind, physicians from the Department of Surgery at the University of Maryland School of Medicine and the R Adams Cowley Shock Trauma Center at the University of Maryland Medical Center (UMMC) have ...
Jun 10, 2013
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After receiving an organ transplant, patients must follow a regimented medication routine to maintain the health of their graft (transplanted organ). Failure to do so, known as non-adherence (NA), can result in life-threatening ...
Jun 4, 2013
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A team of New York Stem Cell Foundation (NYSCF) Research Institute scientists report today the generation of patient-specific bone substitutes from skin cells for repair of large bone defects. The study, led by Darja Marolt, ...
May 6, 2013
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