Neuroscience

How a popular antidepressant drug could rewire the brain

Prozac, the trade name for the drug fluoxetine, was introduced to the U.S. market for the treatment of depression in 1988. Thirty years later, scientists still don't know exactly how the medication exerts its mood-lifting ...

Alzheimer's disease & dementia

Alzheimer's in minibrains

In the majority of cases, dementia can be traced back to Alzheimer's disease. Its causes are not really understood yet. What is known is that plaques form from misfolded proteins and that there is an increase in neuronal ...

Neuroscience

In live brain function, researchers are finally seeing red

For years, green has been the most reliable hue for live brain imaging, but after using a new high-throughput screening method, researchers at the John B. Pierce Laboratory and the Yale School of Medicine, together with collaborators ...

Parkinson's & Movement disorders

Improving cell replacement therapy for Parkinson's disease

Parkinson's disease is a neurodegenerative disease that affects dopamine signaling neurons in patients' brains. Cell-replacement therapy shows some promise as a treatment for Parkinson's. A recent paper in the journal Molecular ...

Neuroscience

iTango: New technique studies neuromodulation in real time

When we think of neuronal communication, we often picture a single neuron releasing molecular neurotransmitters into a junction called a synapse where they stimulate another neuron. But sometimes, instead of crossing a synapse, ...

Neuroscience

Optimized sensors to study learning and memory

Learning and memory are crucial aspects of everyday life. When we learn, our neurons use chemical and molecular signals to change their shapes and strengthen connections between neurons, a process known as synaptic plasticity. ...

Neuroscience

Rabies viruses reveal wiring in transparent brains

Scientists under the leadership of the University of Bonn have harnessed rabies viruses for assessing the connectivity of nerve cell transplants: coupled with a green fluorescent protein, the viruses show where replacement ...

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