News tagged with growth factor receptors
Signature of circulating breast tumor cells that spread to the brain found
Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor ...
Cancer
Apr 10, 2013 |
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Scientists reverse Alzheimer's-like memory loss in animal models by blocking EGFR signaling
A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness ...
Alzheimer's disease & dementia
Sep 24, 2012 |
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New breast cancer genetic alterations discovered
Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...
Cancer
Jun 20, 2012 |
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Researchers say one specific microrna promotes tumor growth and cancer spread
Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in ...
Cancer
Apr 03, 2013 |
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New details on the molecular machinery of cancer
Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor ...
Cancer
Feb 11, 2013 |
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Scientists find a new way to boost common cancer drugs
Shutting down a specific pathway in cancer cells appears to improve the ability of common drugs to wipe those cells out, according to new research from scientists at Fox Chase Cancer Center, published in the January issue ...
Cancer
Jan 14, 2013 |
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Understanding brain tumor growth opens door for non-surgical treatment
One in 25,000 people worldwide is affected by neurofibromatosis type 2 (NF2), a condition where the loss of a tumour suppressor called Merlin results in multiple tumours in the brain and nervous system.
Cancer
Jan 14, 2013 |
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Heart failure in older breast cancer patients linked to medication
Heart failure is a relatively common complication in older women with breast cancer, but the risk is even higher in those patients treated with adjuvant trastuzumab (Herceptin), Yale School of Medicine researchers report ...
Cardiology
Nov 14, 2012 |
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New finding gives clues for overcoming tamoxifen-resistant breast cancer
(Medical Xpress)—A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients ...
Cancer
Nov 02, 2012 |
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PARP inhibitors may have clinical utility in HER2-positive breast cancers
Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive ...
Cancer
Sep 17, 2012 |
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Cancer-causing gene alone doesn't trigger pancreatic cancer, study finds
More than a cancer-causing gene is needed to trigger pancreatic cancer, a study led by Mayo Clinic has found. A second factor creates a "perfect storm" that allows tumors to form, the researchers say. The study, published ...
Cancer
Sep 10, 2012 |
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Modification of tumor suppressor affects sensitivity to potential GBM treatment
Despite years of research, glioblastoma, the most common and deadly brain cancer in adults, continues to outsmart treatments targeted to inhibit tumor growth.
Cancer
Aug 13, 2012 |
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Researchers make progress on early detection of resistance to colorectal cancer drugs
Mutations in a gene called KRAS are causally associated with acquired resistance to targeted therapies for colorectal cancers (CRC), according to new findings from EU-funded researchers from Italy and their ...
Cancer
Jun 25, 2012 |
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Grb2 protein holds powerful molecular signaling pathway in check
Once considered merely a passive link between proteins that matter, Grb2 - pronounced "grab2" - actually lives up to its nickname with its controlling grip on an important cell signaling pathway, scientists at The University ...
Medical research
Jun 22, 2012 |
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New breast cancer drug halts tumor growth better than standard therapy
A new cancer treatment that links chemotherapy with an agent that homes in on specific breast cancer cells was significantly better than the current drug regimen at keeping patients' advanced tumors from progressing, according ...
Cancer
Jun 03, 2012 |
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