News tagged with growth pathway
Scientists discover new target for personalized cancer therapy
A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a ...
Cancer
May 02, 2013 |
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New drug combination therapy developed to treat leukemia
A new, pre-clinical study by researchers at Virginia Commonwealth University Massey Cancer Center suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival ...
Cancer
Apr 17, 2013 |
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A coordinated response to cardiac stress
Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain ...
Cardiology
Mar 01, 2013 |
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Novel combination therapy shuts down escape route, killing glioblastoma tumor cells
Glioblastoma, the most common and lethal form of brain tumor in adults, is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell ...
Cancer
Feb 26, 2013 |
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Study unravels biological pathway that controls the leakiness of blood vessels
(Medical Xpress)—A research team led by scientists at Mayo Clinic in Florida have decoded the entire pathway that regulates leakiness of blood vessels—a condition that promotes a wide number of disorders, such as heart ...
Medical research
Dec 17, 2012 |
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Novel drug therapy targets aggressive form of non-Hodgkin's lymphoma
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma and the seventh most frequently diagnosed cancer. The most chemotherapy resistant form of DLBCL, called activated B-cell – DLBCL ...
Cancer
Dec 10, 2012 |
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Scientists find regulator linking exercise to bigger, stronger muscles
Scientists at Dana-Farber Cancer Institute have isolated a previously unknown protein in muscles that spurs their growth and increased power following resistance exercise. They suggest that artificially raising the protein's ...
Medical research
Dec 06, 2012 |
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Study offers clues to cause of kids' brain tumors
(Medical Xpress)—Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.
Genetics
Nov 16, 2012 |
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Researchers identify novel metabolic programs driving aggressive brain tumors
Researchers at Moffitt Cancer Center have identified metabolic signatures that may pave the way for personalized therapy in glioma, a type of tumor that starts in the brain.
Cancer
Nov 09, 2012 |
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Hedgehog pathway key in tamoxifen-resistant breast CA
(HealthDay)—Noncanonical Hedgehog (Hh) signaling is activated in tamoxifen-resistant tumors, and the phosphoinositide 3-kinase inhibitor/protein kinase B (PI3K/AKT) pathway plays a key role protecting Hh ...
Cancer
Nov 06, 2012 |
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New finding gives clues for overcoming tamoxifen-resistant breast cancer
(Medical Xpress)—A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients ...
Cancer
Nov 02, 2012 |
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Microscopic packets of stem cell factors could be key to preventing lung disease in babies
Researchers at Boston Children's Hospital have found that microscopic particles containing proteins and nucleic acids called exosomes could potentially protect the fragile lungs of premature babies from serious lung diseases ...
Medical research
Oct 31, 2012 |
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Cortex development depends on a protein
As outlined in a study published in Developmental Cell, researchers have discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex.
Medical research
Oct 02, 2012 |
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Researchers find cause of chemotherapy resistance in melanoma
Researchers with UC Irvine's Chao Family Comprehensive Cancer Center have identified a major reason why melanoma is largely resistant to chemotherapy.
Cancer
Sep 17, 2012 |
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At the right place at the right time—new insights into muscle stem cells
Muscles have a pool of stem cells which provides a source for muscle growth and for regeneration of injured muscles. The stem cells must reside in special niches of the muscle for efficient growth and repair.
Medical research
Sep 17, 2012 |
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