Medical research

Study finds immune system is critical to regeneration

The answer to regenerative medicine's most compelling question—why some organisms can regenerate major body parts such as hearts and limbs while others, such as humans, cannot—may lie with the body's innate immune system, ...

Cardiology

Heart muscle disease patients benefit from defibrillator

Some heart disease patients who are treated with cardiac resynchronisation therapy (CRT) would live longer and have fewer hospital admissions if they also received a defibrillator, concludes a team of researchers led by Aston ...

Medical research

New understanding of how muscles work

Muscle malfunctions may be as simple as a slight strain after exercise or as serious as heart failure and muscular dystrophy. A new technique developed at McGill now makes it possible to look much more closely at how sarcomeres, ...

Cardiology

How Gata4 helps mend a broken heart

During a heart attack, blood stops flowing into the heart; starved for oxygen, part of the heart muscle dies. The heart muscle does not regenerate; instead it replaces dead tissue with scars made of cells called fibroblasts ...

Cardiology

How to trick your heart into thinking you exercise

Researchers have discovered that a protein called cardiotrophin 1 (CT1) can trick the heart into growing in a healthy way and pumping more blood, just as it does in response to exercise and pregnancy. They show that this ...

Cardiology

Patching up a broken heart

It is almost impossible for an injured heart to fully mend itself. Within minutes of being deprived of oxygen – as happens during a heart attack when arteries to the heart are blocked – the heart's muscle cells start ...

Medical research

Human heart tissue grown from stem cells improves drug testing

Researchers at the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR have engineered a three-dimensional heart tissue from human stem cells to test the safety and efficacy of new drugs on the heart.

Cardiology

Restoring cardiac function with a matrix molecule

Heart disease remains the leading cause of death worldwide, yet the few available treatments are still mostly unsuccessful once the heart tissue has suffered damage. Mammalian hearts are actually able to regenerate and repair ...

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