Genetics

Pathomechanisms in heart disease discovered

Titin is a "titanically large" protein—the largest in the human body—which enables elastic movements of our muscles, including the heart. Mutations in the titin gene (TTN) that impair this function are the most frequent ...

Cardiology

Finding inspiration to rebuild human heart muscle

Advances in cardiac tissue engineering offer hope for an array of useful applications, from heart repair to disease modeling. As part of active, ongoing research related to bioengineering functional human organs, Adam Feinberg ...

Cardiology

Bio-inspired hydrogel protects the heart from post-op adhesions

A hydrogel that forms a barrier to keep heart tissue from adhering to surrounding tissue after surgery was developed and successfully tested in rodents by a team of University of California San Diego researchers. The team ...

Cardiology

Self-organizing human heart organoids

Biologist Sasha Mendjan at the Austrian Academy of Sciences in Vienna and his team have used human pluripotent stem cells to grow sesame-seed-sized heart models, called cardioids, that spontaneously self-organize to develop ...

Cardiology

Regenerative heart valves and blood vessels a step closer

Non-degradable prostheses for cardiovascular tissues can be used to replace heart valves and blood vessels, but they can't stay in the body permanently. In two recent papers, TU/e researchers in collaboration with a number ...

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