Researchers at Washington University School of Medicine in St. Louis have identified a way to prevent fat cells from growing larger, a process that leads to weight gain and obesity. By activating a pathway in fat cells in ...
Dec 5, 2017
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Medication prescribed for a certain type of epilepsy may offer a new method for treating malignant infantile brain tumors. A specific mTOR inhibitor has the ability to cross the blood-brain barrier to both reach and attack ...
Nov 29, 2019
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St. Jude Children's Research Hospital oncologists have discovered the cell type that gives rise to rhabdomyosarcoma, the most prevalent soft tissue cancer in children. Previously, scientists thought the cancer arose from ...
Jan 8, 2018
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By stirring crosstalk among skin cells that form the roots of hair, researchers report they have regrown hair strands on damaged skin. The findings better explain why hair does not normally grow on wounded skin, and may help ...
Nov 28, 2018
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Immune checkpoint inhibitors are a type of cancer treatment that help the immune system's T cells recognize and attack tumors. But these immunotherapy drugs aren't effective against all cancers. In a study published today ...
Nov 12, 2021
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A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional ...
Sep 20, 2019
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Zinc deficiency - long associated with numerous diseases, e.g. autism, lung cancer, prostate cancer, and ovarian cancers - can lead to activation of the Hedgehog signaling pathway, a biomolecular pathway that plays essential ...
Apr 16, 2015
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(HealthDay)—Odomzo (sonidegib) has been approved by the U.S. Food and Drug Administration to treat patients with locally advanced basal cell carcinoma that has returned despite surgery or radiation, or who are not candidates ...
Jul 25, 2015
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Researchers at Johns Hopkins and the National Institutes of Health have identified a compound that dramatically bolsters learning and memory when given to mice with a Down syndrome-like condition on the day of birth. As they ...
Sep 4, 2013
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Cancer drugs that block a cell-signaling pathway called Hedgehog have shown promise in recent years in treating patients with skin cancer, leukemia and other types of tumors. But the available treatments mostly target the ...
Aug 10, 2016
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