Oncology & Cancer

Pathogens find safe harbor deep in the gastric glands

Scientists have long tried to understand how pathogenic bacteria like Helicobacter pylori, a risk factor for stomach ulcers and cancer, survive in the harsh environment of the stomach. In a new study publishing May 2 in the ...

Medical research

New study explains how inflammation causes gastric cancer

In 1982, researchers reported a link between chronic gastritis and stomach bacterium Helicobacter pylori, triggering a flurry of research into this newly identified pathogen. These studies made it clear that in addition to ...

Oncology & Cancer

Global microbial signatures for colorectal cancer established

Cancers have long been known to arise due to environmental exposures such as unhealthy diet or smoking. Lately, the microbes living in and on our body have entered the stage as key players: while stomach cancer can be caused ...

Medical research

Cancer prevention drug also disables H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

Oncology & Cancer

Probing H. pylori cancer protein

Infection with the stomach-dwelling bacterium Helicobacter pylori— particularly strains producing the oncoprotein CagA—is a strong risk factor for gastric cancer.

Immunology

Toxin floats on lipid rafts

Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...

Diseases, Conditions, Syndromes

Helicobacter pylori infection permanently changes gastric environment

The make-up of the human gut flora is highly individual and extremely diverse. However, when a Helicobacter pylori infection is present, this bacterium displaces all other bacteria in the gastrointestinal tract, leaving only ...

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