Not all cytokine-producing cells start out the same way, study finds
(Medical Xpress)—Cytokines are molecules produced by immune cells that induce the migration of other cells to sites of infection or injury, promote the production of anti-microbial agents, and signal the production of inflammatory ...
Immunology
May 13, 2013 |
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Reassigning cells to fight infection
Just as a uniform helps distinguish a soldier from a police officer, scientists use proteins that immune cells wear on their surfaces to determine their job in the body. T cells, for example, that display ...
Immunology
Apr 26, 2013 |
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Other stomach microbiota modulate resistance to H. pylori-driven ulcers
Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a study published online ahead of pri ...
Immunology
Mar 25, 2013 |
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How the immune system positions its gatekeepers
(Medical Xpress)—For an immune response to get underway, an invading microbe must first be halted in the spleen, and then digested by immune cells known as 'dendritic cells', which guard specific portals. ...
Immunology
Mar 19, 2013 |
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Large-scale Japanese genomics project finds eight new loci linked to atopic dermatitis
Around one in ten Japanese school children suffer from a debilitating form of eczema known as atopic dermatitis (AD). Despite clear signs that the condition is heritable, the genetic origins of the disease ...
Genetics
Feb 22, 2013 |
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New strategy prevents rheumatoid arthritis in mice
Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved ...
Arthritis & Rheumatism
Feb 08, 2013 |
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Finding challenges accepted view of MS: Unexpectedly, damaged nerve fibers survive
(Medical Xpress)—Multiple sclerosis, a brain disease that affects over 400,000 Americans, causes movement difficulties and many neurologic symptoms. MS has two key elements: The nerves that direct muscular ...
Neuroscience
Feb 06, 2013 |
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Team identifies molecular switch enabling immune cells to better fight disease
A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against ...
Immunology
Jan 20, 2013 |
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Researchers elucidate transport pathway of immune system substances
To transport substances from the site of their production to their destination, the body needs a sophisticated transport and sorting system. Various receptors in and on the cells recognize certain molecules, pack them and ...
Immunology
Oct 18, 2012 |
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How immune cells defend themselves against HIV
A team of scientists led by virologists Prof. Oliver T. Fackler and Prof. Oliver T. Keppler from Heidelberg University Hospital have decoded a mechanism used by the human immune system to protect itself from HIV viruses. ...
HIV & AIDS
Oct 02, 2012 |
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Research breakthrough opens door to new strategy for battling HIV
(Medical Xpress)—New research showing how the HIV virus targets "veterans" or memory T-cells could change how drugs are used to stop the virus, according to new research by George Mason University.
HIV & AIDS
Sep 26, 2012 |
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A new starring role for astrocytes
Astrocytes, previously thought of as helper cells for neurons, have recently been shown to send signals themselves. The signals are chemical not electrical and astrocytes send them to neurons, vascular ...
Medical research
Aug 10, 2012 |
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Cell receptor has proclivity for T helper 9 cells, airway inflammation
A research team led by Xian Chang Li, MD, PhD, Brigham and Women's Hospital (BWH) Transplantation Research Center, has shed light on how a population of lymphocytes, called CD4+ T cells, mature into various subsets of adult ...
Immunology
Jul 29, 2012 |
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Under the right conditions, peptide blocks HIV infection at multiple points along the way
Human defensins, aptly named antimicrobial peptides, are made in immune system cells and epithelial cells (such as skin cells and cells that line the gut). One of these peptides, human neutrophil peptide 1, under certain ...
HIV & AIDS
Jul 24, 2012 |
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Helper T cells, not killer T cells, might be responsible for clearing hepatitis A infection
Helper cells traditionally thought to only assist killer white blood cells may be the frontline warriors when battling hepatitis A infection. These are the findings from a Nationwide Children's Hospital study appearing in ...
Diseases, Conditions, Syndromes
Jul 16, 2012 |
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