The molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "double positive" CD4+-CD8+ T cells have lately been discovered in people in various ...
Sep 20, 2022
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Trillions of bacteria and other microbes thrive in our gut microbiomes, and over the last decade, scientists have become increasingly aware of the vital role that they play in creating a healthy gastrointestinal environment. ...
Sep 19, 2022
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Vanderbilt researchers have identified a protein that is key to the "education" of immature T cells in the thymus. The findings, reported in the Journal of Experimental Medicine, could inform therapeutic strategies for enhancing ...
Sep 2, 2022
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People who have often been infected by common cold viruses—which also belong to the coronaviruses—are not better protected against COVID-19, neither after infection with SARS-CoV-2 nor after vaccination. "We already showed ...
Aug 12, 2022
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The Novavax COVID-19 vaccine was approved in Germany this February, followed by the U.S. in mid-July. Immunology professor Martina Sester and her team have now studied how Novavax recipients respond to the vaccine. The study ...
Aug 11, 2022
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In severe COVID-19 patients, metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order ...
Jul 28, 2022
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Scientists from the German Cancer Research Center (DKFZ) studied the human immune response after immunization with the malaria pathogen Plasmodium falciparum. Their goal was to find out against which protein components the ...
Jun 17, 2022
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Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly. One immunotherapy that revitalizes ...
Apr 18, 2022
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In the clinical care of people living with HIV, various types of blood cells are routinely counted to assess the immune system, among them CD4+ cells, or T helper cells, and CD8+ cells, or cytotoxic T cells.
Mar 18, 2022
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New research reveals factors that control the interplay of natural killer (NK) cells—which are part of the body's innate, or first line, immune response—with tumor cells, viral infections, and solid organ transplants. ...
Mar 16, 2022
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