Team identifies molecular switch enabling immune cells to better fight disease
A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against ...
Immunology
Jan 20, 2013 |
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Helper T cells, not killer T cells, might be responsible for clearing hepatitis A infection
Helper cells traditionally thought to only assist killer white blood cells may be the frontline warriors when battling hepatitis A infection. These are the findings from a Nationwide Children's Hospital study appearing in ...
Diseases, Conditions, Syndromes
Jul 16, 2012 |
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Not all cytokine-producing cells start out the same way, study finds
(Medical Xpress)—Cytokines are molecules produced by immune cells that induce the migration of other cells to sites of infection or injury, promote the production of anti-microbial agents, and signal the production of inflammatory ...
Immunology
May 13, 2013 |
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Other stomach microbiota modulate resistance to H. pylori-driven ulcers
Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a study published online ahead of pri ...
Immunology
Mar 25, 2013 |
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How the immune system positions its gatekeepers
(Medical Xpress)—For an immune response to get underway, an invading microbe must first be halted in the spleen, and then digested by immune cells known as 'dendritic cells', which guard specific portals. ...
Immunology
Mar 19, 2013 |
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Large-scale Japanese genomics project finds eight new loci linked to atopic dermatitis
Around one in ten Japanese school children suffer from a debilitating form of eczema known as atopic dermatitis (AD). Despite clear signs that the condition is heritable, the genetic origins of the disease ...
Genetics
Feb 22, 2013 |
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New strategy prevents rheumatoid arthritis in mice
Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved ...
Arthritis & Rheumatism
Feb 08, 2013 |
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Finding challenges accepted view of MS: Unexpectedly, damaged nerve fibers survive
(Medical Xpress)—Multiple sclerosis, a brain disease that affects over 400,000 Americans, causes movement difficulties and many neurologic symptoms. MS has two key elements: The nerves that direct muscular ...
Neuroscience
Feb 06, 2013 |
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Researchers elucidate transport pathway of immune system substances
To transport substances from the site of their production to their destination, the body needs a sophisticated transport and sorting system. Various receptors in and on the cells recognize certain molecules, pack them and ...
Immunology
Oct 18, 2012 |
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Research breakthrough opens door to new strategy for battling HIV
(Medical Xpress)—New research showing how the HIV virus targets "veterans" or memory T-cells could change how drugs are used to stop the virus, according to new research by George Mason University.
HIV & AIDS
Sep 26, 2012 |
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Cell receptor has proclivity for T helper 9 cells, airway inflammation
A research team led by Xian Chang Li, MD, PhD, Brigham and Women's Hospital (BWH) Transplantation Research Center, has shed light on how a population of lymphocytes, called CD4+ T cells, mature into various subsets of adult ...
Immunology
Jul 29, 2012 |
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Rare immune cells could hold key to treating immune disorders
The characterisation of a rare immune cell's involvement in antibody production and ability to 'remember' infectious agents could help to improve vaccination and lead to new treatments for immune disorders, say researchers ...
Immunology
Apr 02, 2012 |
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'Pep talk' can revive immune cells exhausted by chronic viral infection
Chronic infections by viruses such as HIV or hepatitis C eventually take hold because they wear the immune system out, a phenomenon immunologists describe as exhaustion.
Medical research
Dec 13, 2011 |
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Skin sentry cells promote distinct immune responses
A new study reveals that just as different soldiers in the field have different jobs, subsets of a type of immune cell that polices the barriers of the body can promote unique and opposite immune responses against the same ...
Medical research
Jul 21, 2011 |
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New therapeutic targets for virally-induced asthma attacks suggested
When children with asthma get the flu, they often land in the hospital gasping for air. Researchers at Children's Hospital Boston have found a previously unknown biological pathway explaining why influenza induces asthma ...
Diseases, Conditions, Syndromes
May 29, 2011 |
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