News tagged with hematopoietic stem cells

Related topics: stem cells , blood cells , leukemia , bone marrow

Journey from stem cell to blood cell revealed

Researchers have discovered previously undetected steps in the process by which stem cells become blood cells, a process called haematopoiesis.  An international collaboration, including Winthrop Professor Wendy Erber, has ...

Sep 26, 2014
popularity 5 / 5 (2) | comments 0

Two case reports of rare stiff person syndrome

Two female patients achieved clinical remission from the rare, debilitating neurological disease called stiff person syndrome (SPS, which can be marked by a "tin soldier" gait) after an autologous (from your own body) stem ...

Aug 25, 2014
popularity 5 / 5 (1) | comments 0

Key to aging immune system is discovered

There's a good reason people over 60 are not donor candidates for bone marrow transplantation. The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other ...

Jul 31, 2014
popularity 4.8 / 5 (16) | comments 1

Opening-up the stem cell niche

For many years scientists have been trying to unravel mechanisms that guide function and differentiation of blood stem cells, those cells that generate all blood cells including our immune system. The study of human blood ...

Jul 11, 2014
popularity 5 / 5 (3) | comments 0

Hematopoietic stem cell

Hematopoietic stem cells (HSCs) are multipotent stem cells that give rise to all the blood cell types including myeloid (monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells), and lymphoid lineages (T-cells, B-cells, NK-cells). The definition of hematopoietic stem cells has undergone considerable revision in the last two decades. The hematopoietic tissue contains cells with long-term and short-term regeneration capacities and committed multipotent, oligopotent, and unipotent progenitors. Recently, long-term transplantation experiments point toward a clonal diversity model of hematopoietic stem cells. Here, the HSC compartment consists of a fixed number of different types of HSC, each with epigenetically preprogrammed behavior. This contradicts older models of HSC behavior, which postulated a single type of HSC that can be continuously molded into different subtypes of HSCs. HSCs constitute 1:10.000 of cells in myeloid tissue.

This text uses material from Wikipedia licensed under CC BY-SA