News tagged with hematopoietic stem cells

Related topics: stem cells , blood cells , leukemia , bone marrow

Two case reports of rare stiff person syndrome

Two female patients achieved clinical remission from the rare, debilitating neurological disease called stiff person syndrome (SPS, which can be marked by a "tin soldier" gait) after an autologous (from your own body) stem ...

Aug 25, 2014
popularity 5 / 5 (1) | comments 0

Key to aging immune system is discovered

There's a good reason people over 60 are not donor candidates for bone marrow transplantation. The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other ...

Jul 31, 2014
popularity 4.8 / 5 (16) | comments 1

Opening-up the stem cell niche

For many years scientists have been trying to unravel mechanisms that guide function and differentiation of blood stem cells, those cells that generate all blood cells including our immune system. The study of human blood ...

Jul 11, 2014
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One cell's meat is another cell's poison

As a new therapeutic approach, Janus kinases are currently in the limelight of cancer research. The focus of interest is the protein JAK2. By inhibiting this protein one tries to cure chronic bone marrow ...

May 30, 2014
popularity 5 / 5 (1) | comments 0

Can Tai Chi slow the aging process?

Tai Chi, a traditional Chinese martial art and sport, has been found to be beneficial in raising the numbers of an important type of cell when three groups of young people were tested to discover the benefits of Tai Chi, ...

May 28, 2014
popularity 1 / 5 (1) | comments 0

Pushing the boundaries of stem cells

Adults suffering from diseases such as leukemia, lymphoma, and other blood-related disorders may benefit from life-saving treatment commonly used in pediatric patients. Researchers at the Icahn School of Medicine at Mount ...

May 07, 2014
popularity 3 / 5 (2) | comments 0

Hematopoietic stem cell

Hematopoietic stem cells (HSCs) are multipotent stem cells that give rise to all the blood cell types including myeloid (monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells), and lymphoid lineages (T-cells, B-cells, NK-cells). The definition of hematopoietic stem cells has undergone considerable revision in the last two decades. The hematopoietic tissue contains cells with long-term and short-term regeneration capacities and committed multipotent, oligopotent, and unipotent progenitors. Recently, long-term transplantation experiments point toward a clonal diversity model of hematopoietic stem cells. Here, the HSC compartment consists of a fixed number of different types of HSC, each with epigenetically preprogrammed behavior. This contradicts older models of HSC behavior, which postulated a single type of HSC that can be continuously molded into different subtypes of HSCs. HSCs constitute 1:10.000 of cells in myeloid tissue.

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