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Photoacoustic tomography can 'see' in color and detail several inches beneath the skin

Every new imaging technology has an aura of magic about it because it suddenly reveals what had been concealed, and makes visible what had been invisible. So, too, with photoacoustic tomography, which is allowing ...

Medical research created Mar 22, 2012 | popularity 4.9 / 5 (8) | comments 0 | with audio podcast

Mystery of resistance to malaria solved in new study

(Medical Xpress) -- Malaria is a disease caused by parasites passed to humans via the bites of infected mosquitoes. Globally, the disease causes over a million deaths every year, and is especially rife in ...

Medical research created Nov 11, 2011 | popularity 4.8 / 5 (16) | comments 2 | with audio podcast report

Scientists reverse sickle cell anemia by turning on fetal hemoglobin

Not long after birth, human babies transition from producing blood containing oxygen-rich fetal hemoglobin to blood bearing the adult hemoglobin protein. For children with sickle cell disease, the transition from the fetal ...

Medical research created Oct 13, 2011 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Experimental drug achieves unprecedented weight loss

An investigational combination of drugs already approved to treat obesity, migraine and epilepsy produced up to a 10 percent weight loss in obese individuals participating in a one-year clinical trial, according to researchers ...

Medical research created Apr 11, 2011 | popularity 4.3 / 5 (3) | comments 2 | with audio podcast

Why a hereditary anemia is caused by genetic mutation in mechanically sensitive ion channel

A genetic mutation that alters the kinetics of an ion channel in red blood cells has been identified as the cause behind a hereditary anemia, according to a paper published this month in the Proceedings of the National Ac ...

Medical research created Mar 08, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Could an old antidepressant treat sickle cell disease?

(Medical Xpress)—An antidepressant drug used since the 1960s may also hold promise for treating sickle cell disease, according to a surprising new finding made in mice and human red blood cells by a team ...

Medical research created Feb 19, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Creatinine excretion rate linked to higher mortality in T2DM

(HealthDay)—In patients with type 2 diabetes and nephropathy, a lower creatinine excretion rate (CER) is associated with higher all-cause mortality, according to research published online Jan. 8 in Diabetes Ca ...

Diabetes created Feb 12, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study: Blood transfusion associated with increased risk of death for patients with heart attack

A meta-analysis of 10 studies suggests that receipt of a blood transfusion among patients with myocardial infarction (heart attack) was associated with increased all-cause mortality compared with not receiving a blood transfusion ...

Cardiology created Dec 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Discovery of nitric oxide delivery mechanism may point to new avenue for treating high blood pressure

(Medical Xpress)—Researchers at the University of Virginia School of Medicine have shed new light on blood pressure regulation with the discovery of an unexpected mechanism by which hemoglobin controls the delivery of nitric ...

Medical research created Nov 14, 2012 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Laser + bipolar resection helpful for large prostates

(HealthDay)—Bipolar transurethral resection of the prostate (TURP) in combination with high-intensity diode laser (DL + b-TURP) is feasible for treatment of benign prostatic hyperplasia (BPH) in large prostates, according ...

Surgery created Oct 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Eating more legumes may improve glycemic control, lower estimated heart disease risk

Eating more legumes (such as beans, chickpeas or lentils) as part of a low-glycemic index diet appears to improve glycemic control and reduce estimated coronary heart disease (CHD) risk in patients with type 2 diabetes mellitus ...

Health created Oct 22, 2012 | popularity 4.3 / 5 (4) | comments 0 | with audio podcast

Daily vibration may combat prediabetes in youth

Daily sessions of whole-body vibration may combat prediabetes in adolescents, dramatically reducing inflammation, average blood glucose levels and symptoms such as frequent urination, researchers report.

Diabetes created Oct 19, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Might lefties and righties benefit differently from a power nap?

People who like to nap say it helps them focus their minds post a little shut eye. Now, a study from Georgetown University Medical Center may have found evidence to support that notion.

Neuroscience created Oct 17, 2012 | popularity 4.4 / 5 (7) | comments 2 | with audio podcast

No benefit from high-dose multivitamins seen for HIV patients receiving antiretroviral therapy

A new study by Harvard School of Public Health (HSPH) researchers suggests that, for HIV patients receiving highly active antiretroviral therapy (HAART) to treat HIV, there is no benefit from high- vs. standard-dose micronutrient ...

HIV & AIDS created Oct 16, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

'Half-match' bone marrow transplants wipe out sickle cell disease in selected patients

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially-matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painful and debilitating symptoms, ...

Medical research created Sep 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

Hemoglobin

Hemoglobin (English pronunciation: /hiːməˈɡloʊbɪn/; also rendered as haemoglobin and abbreviated Hb or Hgb) is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates, with the exception of the fish family Channichthyidae, as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e., the tissues) where it releases the oxygen to burn nutrients to provide energy to power the functions of the organism, and collects the resultant carbon dioxide to bring it back to the respiratory organs to be dispensed from the organism.

In mammals, the protein makes up about 97% of the red blood cells' dry content, and around 35% of the total content (including water).[citation needed] Hemoglobin has an oxygen binding capacity of 1.34 ml O2 per gram of hemoglobin, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood. The mammalian hemoglobin molecule can bind (carry) up to four oxygen molecules.

Hemoglobin is involved in the transport of other gases: it carries some of the body's respiratory carbon dioxide (about 10% of the total) as carbaminohemoglobin, in which CO2 is bound to the globin protein. The molecule also carries the important regulatory molecule nitric oxide bound to a globin protein thiol group, releasing it at the same time as oxygen.

Hemoglobin is also found outside red blood cells and their progenitor lines. Other cells that contain hemoglobin include the A9 dopaminergic neurons in the substantia nigra, macrophages, alveolar cells, and mesangial cells in the kidney. In these tissues, hemoglobin has a non-oxygen-carrying function as an antioxidant and a regulator of iron metabolism.

Hemoglobin and hemoglobin-like molecules are also found in many invertebrates, fungi, and plants. In these organisms, hemoglobins may carry oxygen, or they may act to transport and regulate other things such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. A variant of the molecule, called leghemoglobin, is used to scavenge oxygen, to keep it from poisoning anaerobic systems, such as nitrogen-fixing nodules of leguminous plants.

For more information about Hemoglobin, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: diabetes , red blood cells