A common drug, already approved by the Food and Drug Administration (FDA), may also be a powerful tool in fighting COVID-19, according to research published this week in Antiviral Research.
Jul 15, 2020
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In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease. Heparin, a common ...
Jul 24, 2020
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A drug used to thin blood has been found to also significantly improve the ability to breathe when inhaled by people with COPD (chronic obstructive pulmonary disease), for which there is no cure.
Dec 1, 2017
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An international team of researchers led by the Universities of Liverpool and Keele, working with Public Health England, has found that the common anticoagulant drug heparin inhibits the SARS-Cov2 virus spike protein, by ...
Jan 28, 2021
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An at-home nasal spray treatment for COVID-19 will be put to the test by Melbourne biomedical researchers, as the University of Melbourne and Monash University receive $4.2 million to establish a six-month clinical trial ...
Dec 28, 2021
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Heparin has long been used as a blood thinner, or anticoagulant, for patients with blood clotting disorders or after surgery to prevent complications. But the medication remains difficult to dose correctly, potentially leading ...
Jan 6, 2023
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An international team of scientists has discovered a molecule that prevents tumor cells spreading from a primary cancer site to colonize other sites in the body.
Jul 25, 2022
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(Medical Xpress)—In "before" and "after" photos from advertisements for wound-healing ointments, bandages and antibiotic creams, we see an injury transformed from an inflamed red gash to smooth and flawless skin.
Feb 20, 2013
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Heparin, a widely available and affordable drug, has found to limit lung damage when inhaled by COVID-19 patients.
Jan 21, 2022
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Robert Linhardt is working to forever change the way some of the most widely used drugs in the world are manufactured. Today, in the journal Science, he and his partner in the research, Jian Liu, have announced an important ...
Oct 27, 2011
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Heparin (from Ancient Greek ηπαρ (hepar), liver), also known as unfractionated heparin, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. It can also be used to form an inner anticoagulant surface on various experimental and medical devices such as test tubes and renal dialysis machines.
Although it is used principally in medicine for anticoagulation, its true physiological role in the body remains unclear, because blood anti-coagulation is achieved mostly by heparan sulfate proteoglycans derived from endothelial cells. Heparin is usually stored within the secretory granules of mast cells and released only into the vasculature at sites of tissue injury. It has been proposed that, rather than anticoagulation, the main purpose of heparin is defense at such sites against invading bacteria and other foreign materials. In addition, it is conserved across a number of widely different species, including some invertebrates that do not have a similar blood coagulation system.
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