Study suggests patients with lung cancer who carry specific HER2 mutations may benefit from certain anti-HER2 treatments
New results from a retrospective study conducted in Europe suggest that anti-HER2 treatments, like the widely used breast cancer agent trastuzumab (Herceptin), have anti-cancer effects in a small subset of patients with advanced ...
Cancer
Apr 22, 2013 |
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New research challenges notion of using Herceptin only for HER2-positive breast cancer
New research from the University of Michigan Comprehensive Cancer Center finds that the protein HER2 plays a role even in breast cancers that would traditionally be categorized as HER2-negative – and that ...
Cancer
Feb 26, 2013 |
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The HER2 paradox: HER2-positive stem cells found in HER2-negative breast cancer
A multicenter study led by researchers at UC Davis describes new, paradoxical characteristics of the most common type of breast cancer. The findings shed light on how the disease can evade treatment and could improve diagnosis ...
Cancer
Dec 14, 2012 |
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Existing drugs may help more breast cancer patients
More patients can benefit from highly effective breast cancer drugs that are already available, according to DNA sequencing studies by researchers at Washington University School of Medicine in St. Louis ...
Cancer
Dec 07, 2012 |
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New target found for cancers resistant to Iressa and Herceptin
A more-sensitive method to analyze protein interactions has uncovered a new way that cancer cells may use the cell-surface molecule HER3 to drive tumor progression following treatment with HER1 and HER2 inhibitors.
Cancer
Sep 04, 2012 |
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Breast cancer treatment shows benefit for women with small, localized disease
Memorial Sloan-Kettering Cancer Center physician-scientists report that women with small, node-negative, HER2-positive breast cancer may obtain a significant benefit from adjuvant chemotherapy with trastuzumab (Herceptin), ...
Cancer
Jun 28, 2011 |
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Protein snapshots reveal clues to breast cancer outcomes
Measuring the transfer of tiny amounts of energy from one protein to another on breast cancer cells has given scientists a detailed view of molecular interactions that could help predict how breast cancer patients will respond ...
Cancer
May 05, 2011 |
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